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Home » Newsletters » BioWorld

BioWorld

April 18, 2014

View Archived Issues

Vital Therapies prices below range as biotech IPOs show growing fatigue

The good news for Vital Therapies Inc. is that the company managed to eke out its initial public offering (IPO) despite the recent selloff in biotechnology stocks. The bad news is that Vital, like two other April graduates, slashed its price to get out the door. The San Diego-based firm raised $54 million, with most of the proceeds slated to fund late-stage trials of Elad, its human cell-based bio-artificial liver system. Read More

Pregnancy test: Nora's $18M series B will fund miscarriage phase II bid

In stealth mode until about six months ago, Nora Therapeutics Inc. raised $18 million in series B cash to expand the development of NT100 into a second phase II trial in women with unexplained recurrent loss of pregnancy. Read More

Agios cues up PK-deficiency fighter AG-348 with first phase I test

Agios Pharmaceuticals Inc. has started a phase I dosing study of its lead candidate for inborn errors of metabolism, AG-348. The experimental treatment for pyruvate kinase (PK) deficiency, a rare inherited metabolic disorder, could help rapidly advance the drug toward a proof-of-concept test in target patients. Read More

Everything you ever wanted to know about fertilization

LONDON – The two molecules, one on the egg and one on the sperm, that interact with each other at the moment of fertilization are now known. Read More

China's BVCF aiming to invest in 20 firms with new $188M fund

HONG KONG – A Chinese investment company focused on health care has secured a third fund to invest $188 million in pharmaceuticals, medical technology, health care services and biotech companies. Read More

Other news to note

Cocrystal Pharma Inc., of Bothell, Wash., said its stock began trading this week under the new symbol COCP, marking the completion of its merger with Biozone Pharmaceuticals Inc., of Englewood Cliffs, N.J. The company is developing antiviral programs, targeting hepatitis C virus, influenza, the human rhinovirus, dengue virus and the norovirus. Read More

Clinic roundup

Stemcells Inc., of Newark, Calif., completed enrollment of the phase I/II trial in spinal cord injury, testing the safety and preliminary efficacy of the HuCNS-SC human neural stem cells. The trial enrolled 12 subjects with chest-level injury to the spinal cord, and seven patients with complete paralysis, who have no motor or sensory functions below the point of injury. Final results from the study are expected to be released mid-2015. Read More

Pharma: Other news to note

Glaxosmithkline plc, of London, said Incruse Ellipta (umeclidinium) received marketing authorization in Canada for the long-term once-daily maintenance bronchodilator treatment of airflow construction in patients with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. The Canadian approval marks the first authorization granted for the product worldwide. Read More

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