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Home » Newsletters » BioWorld

BioWorld

Jan. 10, 2017

View Archived Issues

Takeda's $5.2B bid for Ariad tops flurry of deals to kick off 2017

SAN FRANCISCO – In a sign that could bode well for the industry going into 2017, attendees hadn't even begun plodding through crowded halls at the Westin St. Francis Hotel when a flurry of deals hit the news Monday morning. All of them were dwarfed by Takeda Pharmaceutical Co. Ltd.'s $5.2 billion bid for Ariad Pharmaceuticals Inc. Read More

Good start? Celgene raises 2017 guidance; posts solid 2016 sales

SAN FRANCISCO – As the perennial opener of the J.P. Morgan Healthcare Conference, Celgene Corp.'s early morning presentation generally sets the stage for the annual meeting – and maybe even for the year. Read More

Deals up, dollars down in 2016; diverging trends are unsustainable

SAN FRANCISCO – Coming off a wobbly 2016 – a year when biopharma dealmaking could be viewed as a glass half empty or half full – the direction of the industry this year could hinge on several macro factors, including drug pricing and the ability to improve R&D productivity beyond business development. Read More

Onivyde and conquer? Bet on three Merrimack assets, Ipsen takes others for $1B+

In a potential $1 billion-plus deal that Cowen and Co. analyst Eric Schmidt described as "a necessary and favorable solution" for Merrimack Pharmaceuticals Inc.'s financial straits, the company is selling its approved pancreatic cancer drug Onivyde  and its generic version of Doxil candidate to Ipsen SA. Read More

Moderna unveils multiple pipeline updates

SAN FRANCISCO – Moderna Therapeutics Inc. CEO Stéphane Bancel opened the 35th annual J.P. Morgan Healthcare Conference on Monday by unblinding indications and targets for a raft of before-now veiled candidates in the mRNA specialist's pipeline, five of which are now in the clinic, including its Astrazeneca plc-partnered cardiometabolic candidate, AZD-8601. Read More

Amgen, Immatics in $1B deal to broaden scope of Bite technology

DUBLIN – Immatics Biotechnologies GmbH is getting $30 million up front and could earn more than $1 billion in development, regulatory and commercial milestones from an immuno-oncology alliance with Amgen Inc. focused on developing two bispecific T-cells engager molecules that target intracellular tumor-associated peptide (Tumap) antigens. Read More

Abbvie backs Genomics Medicine Ireland to sequence 45K genomes

DUBLIN – Ireland is entering the genomics era in earnest, on the back of a 15-year alliance between Genomics Medicine Ireland (GMI) Ltd., Abbvie Inc., and Wuxi Nextcode, under which GMI plans to sequence 45,000 genomes in order to uncover new therapeutic targets and pathways relevant to oncology, neuroscience and immunology. Read More

Macrophage to make tumors more susceptible to I-O therapies

LONDON – Macrophage Pharma Ltd. has raised £9 million (US$10.9 million) in a series A to commercialize a small-molecule immuno-oncology technology originally developed by chromatin biology specialist, Chroma Therapeutics Ltd. Read More

Pvp Biologics takes on celiac disease with help from Takeda

HONG KONG – As part of a unique financing and potential acquisition deal, Pvp Biologics, of San Diego, will work with Takeda Pharmaceutical Co. Ltd., of Osaka, Japan, to fund and speed up the development of a new enzyme that can minimize the negative impact of gluten on celiac disease patients. Read More

Regulatory front

Along with its rule on when products made or derived from tobacco will be regulated as drugs, devices or combination products, the U.S. FDA finalized amendments to its regulations about "intended uses." Read More

Financings

Ascentage Pharma Group, of Taizhou, Zhejiang, has raised ¥500 million (US$72 million) from Future Industry Investment Fund, a private equity fund managed by China's State Development & Investment Corporation Fund Management Corp. Ltd. Read More

In the clinic

Bioiberica SA, of Barcelona, reported positive results of the MOSAIC Study (24 MOnth study on Structural changes in knee osteoarthritis Assessed by MRI with Chondroitin sulfate) regarding the use of chondroitin sulfate for knee osteoarthritis. Read More

Other news to note

Pixarbio Corp., of Cambridge, Mass., expanded its non-opiate R&D pain portfolio beyond Neurorelease to include steroid-based injections that can treat acute and chronic pain for up to 90 days. Read More

J.P. Morgan Healthcare Earnings Updates

Acorda Therapeutics Inc., of Ardsley, N.Y., reported the fourth quarter 2016 net sales of Ampyra (dalfampridine) extended-release tablets, 10 mg were $132 million. Full-year net sales amounted to $493 million, an increase of approximately 13 percent over the 2015 net sales. Read More

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