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Home » Newsletters » BioWorld

BioWorld

Jan. 7, 2022

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Andrew Hopkins, CEO, Exscientia

Exscientia lands $5.3B deal expansion with Sanofi

Making good on ambitions to increase its say in the development of drug candidates from its AI-driven discovery platform, as well as the breadth of roles the system serves, Exscientia plc said Jan. 7 it will work with longtime partner Sanofi SA to develop up to 15 new small-molecule candidates for oncology and immunology indications. Sanofi will pay Exscientia $100 million up front and up to $5.2 billion in total milestones, plus tiered royalties, it said. Read More

AZ’s Alexion buys rights to rare heart disease drug from Aduhelm discoverer Neurimmune for $760M

Astrazeneca plc’s recently acquired Alexion Pharmaceuticals Inc. has signed a deal worth up to $760 million with Neurimmune AG, the Swiss biotech that discovered Alzheimer’s drug Aduhelm (aducanumab), buying rights to amyloidosis drug NI-006. While Biogen Inc.’s Aduhelm targets amyloid plaques thought to cause Alzheimer’s in the brain, the phase Ib drug in Alexion’s deal is intended to tackle the build-up of the rogue protein that causes heart disease caused by transthyretin amyloid cardiomyopathy (ATTR-CM). Read More
Globe and currency symbols

Final tally comes in at $118B, second top financings amount in biopharma history

While the $118.3 billion raised by biopharma companies in 2021 through public and private transactions is 12% lower than the amount raised the prior year, it still represents an impressive financings record, led primarily by IPOs and venture capital rounds. Read More
IPO puzzle pieces

Trio of biopharma IPOs open new year

Three biopharma IPOs rounded out the first week of the new year, with Amylyx Pharmaceuticals Inc., Cincor Pharma Inc. and Vigil Neuroscience Inc. all pricing new Nasdaq issues Dec. 7. Taken together, the offerings raised about $482 million, though all received cool receptions, with only the most mature among them, Amylyx, (NASDAQ:AMLX) holding its ground at midday. Read More
Woman sleeping

Scheduling conflict? Harmony’s Wakix, not bound by DEA, targets Xywav share in IH

Harmony Biosciences Holdings Inc.’s plan disclosed at the start of last December to launch a phase III study with Wakix (pitolisant) for idiopathic hypersomnia (IH) during the first half of this year brought renewed attention to the sleep space, where a handful of players are jostling for position. Read More

Appointments and advancements for Jan. 7, 2022

New hires and promotions in the biopharma industry, including: Adverum, Merck, Rani. Read More

Financings for Jan. 7, 2022

Biopharmas raising money in public or private financings, including: AN2, Coherus, Cytokinetics, Verisim Life, Viscogliosi Brothers Acquisition . Read More

In the clinic for Jan. 7, 2022

Clinical updates, including trial initiations, enrollment status and data readouts and publications: 23andme, Adlai, Affimed, Aligos, Anokion, Avalo, Bluerock, BMS, Bolt, Curis, First Wave, In8bio, Intellia, Nanobiotix, Nimbus, Obseva, Puretech, Rafael, Regeneron, Sapience, Scisparc, SK, Sutro. Read More

Other news to note for Jan. 7, 2022

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Absci, Astellas, Basilea, Contrafect, Cybin, GSK, Hepion, Immuneering, Janssen, Kinnate, Merck, Qiagen, Redhill, Regeneron, Sangamo, Sanofi, Synairgen, Syneurx, Trexbio, Ultragenyx, Valo, Vir. Read More

Regulatory actions for Jan. 7, 2022

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Akeso,  Astex, Atyr, Beigene, Freeline, Jubilant, Otsuka, Pharming, Regenxbio, Vaxcyte, Zai.

Read More

Money raised by biopharma: 2021 vs. 2020 vs. 2019

Total raised in public, private and other financings of biopharma companies, comparing 2021 vs. 2020 vs. 2019. Read More

Biopharma money raised: Jan. 1-Dec. 30, 2021

Year-to-date money raised in public, private and other financings of biopharma companies. Read More
Hand holding IPO, financial icons

Biopharma money raised by quarter in 2021 (US$M)

Biopharma money raised to-date and by quarter in 2021, including public, private and other financings. Read More

BioWorld and Nasdaq stock indices

These graphs compare the performance of the biotech stocks for all of 2021 using the BioWorld Stock Indicator and the Nasdaq Biotech Index. Read More

Biggest gainers and losers for the week of Jan. 3-7, 2022

The top 10 biopharma stock gainers and losers for the week. Read More

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