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Home » Newsletters » BioWorld

BioWorld

Aug. 26, 2022

View Archived Issues
Gavel and vials

Moderna lawyers up against Pfizer-Biontech in COVID-19 patent dispute

Three of the biggest COVID-19 vaccine developers are heading into a legal battle. Moderna Inc. said it has filed lawsuits alleging the Pfizer Inc.-Biontech SE Comirnaty vaccine infringes patents Moderna filed between 2010 and 2016 that cover its mRNA technology. Pfizer and Biontech “unlawfully” copied the technology without permission, according to Moderna. Read More

New solution fur cancer tox? Mink advancing invariant killer Ts

How to get reasonable efficacy in cancer without toxicity – problematic especially in older patients – is a dilemma made ever more poignant by the advent of CAR T therapies and bispecific antibodies, which have been showing overall response rates of about 70%, but with side effects that can severely limit their use. Invariant natural killer T cells may provide an answer, and New York-based Mink Therapeutics Inc. aims to find out. Read More
Natural killer cell

Japan’s Healios advances its iPSC-derived gene engineered killer cells toward the clinic

Japan’s Healios K.K. is in discussions with Japan’s Pharmaceutical and Medical Devices Agenc about the regulatory path forward for its Multistem somatic stem cell products, for which it conducted phase II/III trials in ischemic stroke and a phase II trial in acute respiratory distress syndrome. Read More

Lee’s Pharm acquires lucinactant from Windtree in $78.9M deal

Lee’s Pharmaceutical (HK) Ltd. and its affiliate, Zhaoke Pharmaceutical (Hefei) Co. Ltd., expanded their rights to lucinactant Surfaxin, lyophilized lucinactant Surfaxin LS and Aerosurf from Windtree Therapeutics Inc. in a $78.9 million global license deal to develop and commercialize the candidates for the treatment of preterm infants with respiratory distress syndrome and other potential indications. Read More
Clinical data illustration

Nuvalent’s kinase inhibitors make the leap to the clinic

Having initiated its first two clinical trials in non-small-cell lung cancer since January, Nuvalent Inc. said it expects to unveil preliminary dose-escalation data before year-end. Ahead of the data, Nuvalent's phase I/II Arros-1 trial evaluating NVL-520, a kinase inhibitor, in patients with advanced ROS1-positive NSCLC and other solid tumors, continues to enroll participants. Read More
Arrow-down.png

Clinical data down 16%; cancer remains a stronghold

With financings, U.S. FDA approvals and mergers and acquisitions all tracking behind last year, why would clinical data be any different? According to BioWorld research, clinical trial reports are down by 16.2% this year. The number of efforts targeting the COVID-19 pandemic, as well as the proportion of data focused on infectious diseases, are also dropping. Read More

Appointments and advancements for Aug. 26, 2022

New hires and promotions in the biopharma industry, including: Cognesy, Frontier Medicines, Vaxart. Read More

Financings for Aug. 26, 2022

Biopharmas raising money in public or private financings, including: Assertio, Biovaxys, Mendus, Navidea, Paxmedica, Viridian. Read More

In the clinic for Aug. 26, 2022

Clinical updates, including trial initiations, enrollment status and data readouts and publications: AB Science, Astrazeneca, Biomarin, Biontech, Century, Erytech, Iovance, Janssen, Moderna, Pfizer, Savara, Therapeutic Solutions. Read More

Other news to note for Aug. 26, 2022

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Avadel, AVM, Biocryst, Biocytogen, Clearmind, Elevatebio, Emerald, Finch, Jazz, Merck & Co., Skye, Stoke, Takeda. Read More

Regulatory actions for Aug. 26, 2022

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: AB Science, Astrazeneca, Biomarin, Biontech, Century, Erytech, Iovance, Janssen, Moderna, Pfizer, Savara, Therapeutic Solutions. Read More

Money raised by biopharma: 2022 vs. 2021 vs. 2020 vs. 2019

Total raised in public, private and other financings of biopharma companies, comparing 2022 vs. 2021 vs. 2020 vs. 2019. Read More

Biopharma money raised: Jan. 1-Aug. 25, 2022

Year-to-date money raised in public, private and other financings of biopharma companies. Read More

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