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Home » Newsletters » BioWorld

BioWorld

Jan. 12, 2023

View Archived Issues
Oral medication

Oramed quits oral insulin development in type 2 diabetes after phase III failure

Oramed Pharmaceuticals Inc. has had a lot of success with testing its oral insulin, until now. The company will discontinue it oral insulin clinical work in treating type 2 diabetes after ORMD-0801 failed to hit its phase III study’s primary and secondary endpoints. The late-stage stumble clobbered the company stock (NASDAQ:ORMP), which lost 76% of its value on Dec. 12 to close at $2.54 each. Read More
Deal-handshake-wire-frame.png

Shy of the prior year, deals reach $206B in 2022; M&As fall behind by 36%

While it made a sturdy effort as biopharma companies opted for licensing deals over M&As in 2022, the year did not surpass 2021 in deal values, falling about 3.5% short. Lackluster M&A values dropped to their lowest levels in five years and were down by 35.6% compared with 2021. Read More
Streptococcus pneumoniae in lungs

Biopharmas at full strain to find broader PCVs; Vaxcyte, GSK, Merck in play

Although strides have been made in the space, biopharma’s hunt for a wider net to cast in vaccines for pneumococcal disease has recruited the likes of Vaxcyte Inc., GSK plc and Merck & Co. Inc., each racing for a candidate with improved valence. Read More

First rounds of US price negotiations to center on Price D drugs

Although the U.S. Inflation Reduction Act charges the Centers for Medicare & Medicaid Services with negotiating prices of the Part B and D drugs with the highest Medicare spend, the first two rounds of negotiations will focus solely on Part D drugs, which are dispensed through pharmacies. Read More
Brain activity concept illustration

Common network found across multiple psychiatric disorders

A psychiatric disorder rarely comes alone. More than half of all individuals who meet the diagnostic criteria for any psychiatric disorder are diagnosed with more than one condition. That high degree of comorbidity is often viewed as a consequence of the heterogeneity of psychiatric disorders – and as evidence that psychiatric diagnoses poorly reflect the underlying brain biology. Data published in Nature Human Behaviour on Jan. 12, 2023, has identified another likely contributor to the high degree of overlap between different psychiatric disorders. Read More

Appointments and advancements for Jan. 12, 2023

New hires and promotions in the biopharma industry, including: Biostage, Jupiter, Mallinckrodt, Relmada, Senda, Ventyx. Read More

Financings for Jan. 12, 2023

Biopharmas raising money in public or private financings, including: Opgen, Palvella, Revive. Read More

In the clinic for Jan. 12, 2023

Clinical updates, including trial initiations, enrollment status and data readouts and publications:  Aclaris, Alvotech, Aprea, Bexion, Bio4t2, Bioxcel, Glaukos, Grifols, Hemab, Hightide, Lipella, Nascent, Panbela, Prokidney, Zenas. Read More

Regulatory actions for Jan. 12, 2023

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Astrazeneca, Avillion, Eisai, Intellia, SFA, Takeda, Union. Read More

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