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Home » Newsletters » BioWorld

BioWorld

Nov. 22, 2023

View Archived Issues
Cells and DNA helix

‘A trillion in each of us’: Flagship-backed Quotient takes on somatic genomics

Launching a company based on knowledge that “the fundamental principle that most people hold to be true is off by a trillion” is a rare opportunity, said Jake Rubens, co-founder and president of Quotient Therapeutics Inc., a company that emerged from stealth this week, backed by two years of platform development and a $50 million investment from Flagship Pioneering. Read More

DMC turns over phase III Index card in UC, shares plummet

Index Pharmaceuticals Holding AB CEO Jenny Sundqvist said liquidation of the company in the wake of phase III data with cobitolimod in moderate to severe ulcerative colitis (UC) is “one of the options that will be on the table.” Shares of the Stockholm-based firm (STO:INDEX) closed Nov. 22 at SEK0.24 (US2 cents), down SEK0.41, or 63%, on word that an independent data monitoring committee (DMC) has completed the planned dose-selection analysis, including safety review and assessment for futility, of induction Study 1 of the phase III program called Conclude, testing the Toll-like receptor 9 agonist cobitolimod. The DMC concluded that Index’s lead compound is unlikely to meet the primary endpoint, and the company said development will be stopped. Read More
Gold dollar sign inside gold cog

Syncona taking Freeline private in $28.3M deal

Freeline Therapeutics plc is being taken private by its founding investor and majority shareholder Syncona Ltd, in an all-cash transaction that values the Nasdaq-listed gene therapy specialist at $28.3 million. Syncona also will provide up to $15 million cash to keep Freeline afloat as it awaits the next tranche of data on its lead program FLT-201, which is positioned as a one-off treatment for the lysosomal storage disorder, Gaucher’s disease. Read More
Illustration of pill being analyzed

Blueprint Medicines up on Q3 results amidst broader drug developer decline

BioWorld’s Drug Developers Index continued to fall in October, down 31.4% for the year, compared to September when it ended down 22.8%. Among the 30 stocks tracked, only five saw gains, with the remaining 25 experiencing declines, aligning with the year’s overall trend through Nov. 16. In March, the index experienced a 12.56% drop, stayed around negative 12% through July, and has faced steady declines since. Read More
Handshake_global2.png

Simcere licenses China rights to Connect’s rademikibart in $120M deal

Connect Biopharma Holdings Ltd. has been seeking a partner for its atopic dermatitis candidate rademikibart, and it appears to have found the perfect partner in Simcere Pharmaceutical Group, which gains exclusive rights to develop, manufacture and commercialize rademikibart in China in a deal worth $120 million plus royalties. Read More

Boehringer buying T3 Pharma for $508M

Boehringer Ingelheim GmbH has acquired T3 Pharmaceuticals AG for CHF450 million (US$507.5 million) to gain access to a technology that uses live bacteria to deliver immune-modulating proteins to cancer cells and tumor microenvironments. Read More
Stethoscope.png

Clinical trial updates up nearly 5% through October

Clinical trial updates for the period of January to October 2023 saw an increase of 4.6% compared to the same time period last year. Comparatively, clinical data from January to September 2023 was up 1.79% compared to the same period last year. Read More

Holiday notice

BioWorld's offices will be closed in observance of Thanksgiving in the U.S. No issues will be published Thursday, Nov. 23, or Friday, Nov. 24. Read More

Appointments and advancements for Nov. 22, 2023

New hires and promotions in the biopharma industry, including: Relief, Sutro. Read More

Financings for Nov. 22, 2023

Biopharmas raising money in public or private financings, including: Can-Fite, Oryzon, Vivodyne. Read More

In the clinic for Nov. 22, 2023

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aerovate, Ainos, Can-Fite, Chengdu Origen, Connect, Edesa, Galmed, GSK, Kazia, Landos, Morphosys, Pharming, Sapient, Vanotech, Xspray, Zyua. Read More

Other news to note for Nov. 22, 2023

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Algernon, Bristol Myers, Evelo, Gradalis, J&J, March, Medicine, Merck, Scisparc, Seyltx, SK Bioscience. Read More

Regulatory actions for Nov. 22, 2023

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Biocryst, Biostar, Foundation, Immix, Nevragenics, Nexcella, Senhwa. Read More

Money raised by biopharma

Total raised in public, private and other financings of biopharma companies, comparing 2019-2023.

Read More

Biopharma money raised: Jan. 1-Nov. 21, 2023

Year-to-date money raised in public, private and other financings of biopharma companies. Read More

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