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Home » Newsletters » BioWorld

BioWorld

July 31, 2024

View Archived Issues
Stock chart, red down arrow

Mayday, skipper: Pepgen shares run aground on DMD phase II data

Pepgen Inc. fell slightly short of its phase II dystrophin goal with PGN-EDO51 for patients with Duchenne muscular dystrophy (DMD) whose mutations are amenable to an exon 51-skipping approach, but Wall Street reacted in a big way, sending the Boston-based firm’s stock (NASDAQ:PEPG) down 33%, or $5.55, to close July 31 at $11.43. Read More

New FDA adcom to consider Niemann-Pick drug at debut meeting

Zevra Therapeutics Inc. will make its case Aug. 2 for its Niemann-Pick type C (NPC) candidate, arimoclomol, when the U.S. FDA’s Genetic Metabolic Diseases Advisory Committee (GeMDAC) meets for the first time. Read More
Hand between blocks

Fibrogen drops pamrevlumab after latest failure, slashes workforce

The disappointments continue for Fibrogen Inc., which is terminating work on its once-promising anti-CTGF monoclonal antibody, pamrevlumab, after reporting missed endpoints in two late-stage pancreatic cancer studies, and cutting its workforce by about 75%. Read More

Macrogenics stock plunges again after more Tamarack trouble

Macrogenics Inc., agreeing with an independent data monitoring committee, has discontinued dosing patients in the troubled phase II Tamarack study of vobramitamab duocarmazine as a second-line treatment for metastatic castration-resistant prostate cancer. Read More
The Nasdaq Stock Exchange headquarters in New York

Radiopharm Theranostics to list on Nasdaq by year-end

Radiopharm Theranostics Ltd. said it plans to list on Nasdaq by the end of 2024. The company had earlier announced plans to list in February 2023, but it delayed the listing due to market conditions.

Read More

BioWorld Insider Podcast: The first half of 2024 was strong as M&As and financings dominate

Karen Carey, BioWorld managing editor and chief analyst, takes a look at the numbers from the first half of 2024. She finds the first six months to be healthy for the biopharma market while the rest of the year is populated with question marks that include the U.S. presidential election and potential interest rate cuts. Read More

‘We're always on the lookout for what's next’

From no hope to viable treatments, BioWorld  is there to cover the breakthroughs in medicine. Listen to Randy Osborne explain why the BioWorld  team is ‘always on the lookout for what's next.’ Read More

Appointments and advancements for July 31, 2024

New hires and promotions in the biopharma industry, including: Abcuro, Bit.bio, Immatics, Mural Oncology, Nine Square, Santhera. Read More

Financings for July 31, 2024

Biopharmas raising money in public or private financings, including: Arch Biophartners, Chemomab, Day One, LTZ, Novabay, Pinetree, Synthetica. Read More

In the clinic for July 31, 2024

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aspargo, Biontech, Celldex, Clearside, Imunon, Nkgen, Novo Nordisk, Roche Holding, Yamo. Read More

Other news to note for July 31, 2024

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Cortice, CNS Pharmaceuticals, Leveragen, Moderna, Mthera, Neurobo, Neutherx, VBI Vaccines, Verseon. Read More

Regulatory actions for July 31, 2024

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Amneal, Bio-Thera, Clearside, Dr. Reddy's, Galderma, Kiora, Neurim, Parvus, Stallergenes, Verastem. Read More

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