Although last year’s massive U.S. launch of Humira biosimilars captured headlines, the market adoption of those competitors has been nothing to write home about, even with discounts as low as 85% off the innovator price. Read More

Potential implications for others in the space, including Pfizer Inc. and Bridgebio Pharma Inc., became the subject of buzz after Alnylam Pharmaceuticals Inc. provided details from the Helios-B phase III study with RNAi candidate vutrisiran, in the works for ATTR amyloidosis with cardiomyopathy.

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After initially reporting that Xanamem failed to meet the primary endpoint in cognitive attention in the phase IIa Xanacidd cognition and depression trial, Actinogen Medical Ltd. CEO Steven Gourlay said a new analysis shows clinically and statistically significant benefits in depression. Read More

Through July 2024, biopharma firms received $2.52 billion in grants, marking a 52% increase from $1.66 billion in grants during the same period last year. However, nonprofit deals are at their lowest level on record, according to BioWorld’s records. Although nonprofit deal values were initially higher in April compared to 2023, they have since dropped and are now well below the levels seen in prior years. Read More

Artificial intelligence (AI) drug discovery company Noetik Inc. has closed on an oversubscribed $40 million series A financing round. The company plans to use the money to expand its atlas of human cancer biology with its in vivo CRISPR platform to advance a pipeline of cancer therapeutics to the clinic. In describing its approach, the company said that making a genuine impact on drug discovery requires computational capabilities to understand and simulate disease biology at the patient level, identifying the right targets and matching them with the right therapies. Read More

BioWorld's offices will be closed in observance of Labor Day in the U.S. No issue will be published Monday, Sept. 2. Read More

Total raised in public, private and other financings of biopharma companies, comparing 2019-2024. Read More

Year-to-date money raised in public, private and other financings of biopharma companies. Read More

New hires and promotions in the biopharma industry, including: Hookipa, Ventyx. Read More

Biopharmas raising money in public or private financings, including:  Aprinoia, Avicanna, Betterlife, Geovax Labs, TC Biopharm. Read More

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Gain Therapeutics, Merck. Read More

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Biocon Biologics, Biomarin, Janssen, Johnson & Johnson, Repare. Read More

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: GSK, Janssen, Nuvectis, Scilex. Read More