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Home » Newsletters » BioWorld

BioWorld

Nov. 7, 2024

View Archived Issues
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Sales balloon for GLP-1 drugs from Novo Nordisk, Eli Lilly

Nearly $3.8 billion was earned by Novo Nordisk A/S and Eli Lilly and Co. in the third quarter for their glucagon-like peptide-1 (GLP-1) drugs to treat obesity. Novo’s GLP-1 drug, Wegovy (semaglutide), approved by the U.S. FDA in June 2021, had sales of DKK17.3 billion (US$2.5 billion), while Lilly’s Zepbound (tirzepatide), which is a GLP-1 and glucose-dependent insulinotropic polypeptide dual agonist FDA-approved in November 2023, posted sales of $1.26 billion for the quarter. Read More
Close up of senior man holding wrist of arthritic hand

Lilly bid wilts as others forge on with PD-1 in RA

Eli Lilly and Co.’s chief scientific officer, Daniel Skovronsky, called peresolimab, the PD-1 agonist previously in the works by the firm for rheumatoid arthritis (RA), a “really interesting mechanism” – but not interesting enough. Read More
Liver illustration

GLP-1s push into MASH as semaglutide 2.4 mg hits endpoints

Positive findings from a phase III trial of semaglutide in metabolic dysfunction-associated steatohepatitis (MASH) is moving Novo Nordisk A/S to expand the glucagon-like peptide-1 (GLP-1) agonist’s indications in the U.S. and Europe, the Danish pharma said, as the MASH field sights more novel therapies. Read More

Californians say yes to 340B accountability measure

With the U.S. Congress sitting on its hands on reforms to the 340B drug discount program, states are stepping into the gap. While most state efforts have been aimed at forcing biopharma companies to give the federally mandated drug discounts to an increasing number of contract pharmacies, California is looking in a different direction. According to unofficial election results, a slim majority of the state’s voters said yes to Proposition 34, which would require certain providers that benefit from the drug discounts to spend at least 98% of their 340B revenues on direct patient care. Read More
Endometriosis

Blocking CGRP in endometriosis: two birds with one stone?

Researchers at Harvard Medical School have found that blocking the neuron-released peptide CGRP decreases pain sensitivity and reduces lesion size in endometriosis. Endometriosis is a painful, steroid-dependent inflammatory condition in which tissue similar to that of the endometrial lining grows and establishes outside the uterine mucosa. Read More

Appointments and advancements for Nov. 7, 2024

New hires and promotions in the biopharma industry, including: Aurinia, Quotient, Synox. Read More

In the clinic for Nov. 7, 2024

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Alligator, Lexicon, Minghui, Qurebio, Tango, Ultragenyx. Read More

Other news to note for Nov. 7, 2024

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Acadia, Adnexus, Lisata, Neuren, Solascure, Valo. Read More

Regulatory actions for Nov. 7, 2024

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Nanjing Leads, Sanofi, Regeneron. Read More

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