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Home » Newsletters » BioWorld

BioWorld

Nov. 26, 2024

View Archived Issues
M&A letters over missing puzzle pieces

Roche snaps up Poseida for $1.5B

Poseida Therapeutics Inc. is being bought out for $1.5 billion by partner Roche Holdings Inc. to develop allogeneic CAR T therapies to treat hematologic malignancies. The two companies began their collaboration in August 2022, a deal that brought Poseida $110 million up front and another $110 million in near-term milestone payments. With the acquisition, Roche plans to develop CAR T programs for solid tumors and autoimmune diseases with Poseida's genetic engineering platform and preclinical programs. Read More

Sarepta ‘secures future’ with massive Arrowhead collaboration

In the largest collaboration of 2024, Sarepta Therapeutics Inc. and Arrowhead Pharmaceuticals Inc. entered a sprawling global licensing deal that includes a swath of clinical and preclinical candidates targeting rare genetic diseases. Under the terms, Sarepta gains access to existing and potential future compounds derived from the RNAi platform developed by Arrowhead, with the latter eligible for payments potentially exceeding $11 billion. Read More
Tape measure wrapped around scale

No plateau: Street level-sets obesity on Amgen Maritide phase II

Wall Street began comparing and contrasting what’s available after Amgen Inc. rolled out phase II data with weight loss candidate Maritide – a disclosure that led shares of the biotech heavyweight (NASDAQ:AMGN) to close Nov. 26 at $280.01, down $13.99. Read More

Historic or empty gesture? CMS proposes covering obesity drugs

When U.S. CMS Administrator Chiquita Brooks-LaSure announced Nov. 26 that the agency is “reinterpreting” the law in proposing a rule allowing Medicare and Medicaid to cover obesity drugs beginning in 2026, she called it a “historic step.” The rule, if finalized, could make obesity drugs like Novo Nordisk A/S’ Wegovy (semaglutide) and Eli Lilly and Co.’s Zepbound (tirzepatide) available to millions more Americans and further invigorate development of other obesity drugs. But given the lateness of the day in the Biden administration, the proposal may be more symbolic than historic. Read More
Illustration of muscle tissue anatomy

Dystrophies affect not just muscles; can RNA editing help?

At the Breakthroughs in Muscular Dystrophy special meeting held in Chicago Nov. 19-20, 2024, and organized by the American Society of Gene & Cell Therapy (ASGCT), multiple interventions at the RNA level were among the approaches that were presented to fight muscular dystrophies. Read More
Antibodies attacking virus cell

Novavax and Assembly lead infectious disease gainers in 2024

The BioWorld Infectious Disease Index has struggled to gain ground in 2024 but has held relatively steady in recent months. After ending July down 7.66%, it closed October down 12.07% and sat at an 8.86% decline for the year as of Nov. 22.  Read More
Group of multigenerational, multiracial women

Healing the health divide: BioWorld reports on women’s health space

It’s difficult to fathom that the health of half the world’s population is underserved. But it’s a hard truth. Women’s health has traditionally focused on what Seema Kumar, the CEO of Cure, coined as the “bikini zone.” However, reproduction and breast health are a drop in the bucket when it comes to women’s health. In this multipart, in-depth series, BioWorld provides insight into the oft-overlooked space of women’s health, exposing the disparities in research and funding while looking toward future opportunities for bridging the gender gap in health care. Read More

BioWorld Insider podcast: Healing the health divide for women

Karen Carey, BioWorld’s managing editor and chief analyst, and Anette Breindl, managing editor of Bioworld Science, join this episode of the BioWorld Insider podcast to talk about the business and the science of women’s health. Read More

Appointments and advancements for Nov. 26, 2024

New hires and promotions in the biopharma industry, including: Kalvista, Neuronos. Read More

Financings for Nov. 26, 2024

Biopharmas raising money in public or private financings, including: Adcendo, Doron, Eyenovia, Kanglin. Read More

In the clinic for Nov. 26, 2024

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Astrazeneca, Biohaven, Blue Lake, Cassava, IGC, Immix, In8bio, Merck & Co., Orbus, Plus, SCG. Read More

Other news to note for Nov. 26, 2024

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Advantage, Aelix, Eton, Gilead, Klothea. Read More

Regulatory actions for Nov. 26, 2024

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Alnylam, Bridgebio, Citius, GSK, Imunon, Intellia, Shorla. Read More

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