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Home » Newsletters » BioWorld

BioWorld

April 23, 2025

View Archived Issues
SPAC ticker illustration

Veraxa through a SPAC heads to Nasdaq

Veraxa Biotech AG is merging with special purpose acquisition company (SPAC) Voyager Acquisition Corp. to become a publicly traded company that will develop treatments for solid tumors. Read More
deal-handshake2

Chinabio 2025: Europe-China pharma deals rise as US markets shut

Europe was a bigger counterpart to China in pharmaceutical dealmaking than the U.S. last year, speakers at Chinabio Partnering Forum said April 23, and the trend is likely to continue in 2025 with the shuttering of U.S. capital and volatility ailing global markets. Read More
Telomeres and DNA illustration

Tessellate signs $570M Boehringer deal targeting ALT-positive cancers

Synthetic lethality specialist Tessellate Bio NV has closed its first deal, agreeing to a €500 million-plus (US$570 million) research and license agreement with Boehringer Ingelheim GmbH, to develop small molecules targeting tumors that depend on alternative lengthening of telomeres (ALT) for their growth. Read More
Female healthcare professional holding health icon

US HHS axes women’s health research

On Jan. 21, economist Jay Bhattacharya spoke publicly for the first time since becoming the current NIH director, addressing the NIH Council of Councils in an open session. The goal of Bhattacharya’s remarks seemed to be to reassure troubled staffers. His reassurances, however, were given in the face of another blow to NIH research. Read More
World map with supply chain icons

Free trade zones not a simple workaround for tariffs

If U.S. sectoral tariffs on biopharmaceuticals become a reality and most country-by-country tariffs on other medical products resume, manufacturers may have to rethink their use of U.S. free trade zones to turn foreign-sourced active pharmaceutical ingredients and other components into finished products for the U.S. market. Read More

China adds Ascentage's lisaftoclax, olverembatinib to guidelines

Ascentage Pharma Group Corp. Ltd. said two of its novel candidates have been included in the 2025 Chinese Society of Clinical Oncology Guidelines, including its in-house developed Bcl-2 selective inhibitor, lisaftoclax (APG-2575), which is under review in China and could be the first domestically approved Bcl-2 inhibitor and the second global approval. Read More

US FDA reduction-in-force delays response to Vanda

A U.S. FDA CDER official is among the first to say the quiet part out loud in proposing a Sept. 12 deadline for the agency to respond to Vanda Pharmaceuticals Inc.’s request for summary judgment or a hearing on CDER’s refusal to approve tradipitant to treat gastroparesis. Read More

The BioWorld Insider podcast: Bracing for the impact of tariffs and grant cuts

As pharma deals with the impact of U.S. NIH grant cuts and the imposition of tariffs, a lot of pressure is shifting to smaller and midcap companies, according to two executives who spoke on the newest BioWorld Insider podcast. Read More

Appointments and advancements for April 23, 2025

New hires and promotions in the biopharma industry, including: Aeon, Cassava, Galapagos, Geovax, Halda, Piezo, Tagworks, Telix. Read More

Financings for April 23, 2025

Biopharmas raising money in public or private financings, including: Aptevo, Genrab, Sirona. Read More

In the clinic for April 23, 2025

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Achieve, Cellphire, Ferring, Lipella, Metavia, Novadip. Read More

Other news to note for April 23, 2025

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: 1st Bio, ACM, Chimerix, Diosynvax, Jazz, Ligachem. Read More

Regulatory actions for April 23, 2025

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Ascentage, Brainchild, Neuronos, OS. Read More

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