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BioWorld - Monday, January 12, 2026
Home » Newsletters » BioWorld

BioWorld

Oct. 22, 2025

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Antibodies attacking cancer cell

Innovent rings up $11.4B deal with Takeda for three I-O/ADC assets

Takeda Pharmaceutical Co. Ltd. agreed to codevelop and commercialize up to three of Innovent Biologics Co. Ltd.’s immuno-oncology (I-O) and antibody-drug conjugate (ADC) candidates with the signing of a $11.4 billion deal, including $1.2 billion paid up front. Read More
Gold dollar sign inside gold cog

No nap gap: Alkermes to sleep market early via $2.1B Avadel buy

Having reached peace with Jazz Pharmaceuticals plc over litigation related to its U.S. FDA-approved drug, Lumryz (sodium oxybate), Avadel Pharmaceuticals plc agreed to a cash takeover by Alkermes plc valued at about $2.1 billion, a deal Alkermes CEO Richard Pops said “puts us in the sleep market immediately on closing,” which is expected in the first quarter of 2026. All three players are based in Dublin. Read More
Red arrow pointing downward on a stock market ticker

Alector stock and staff halved after phase III fail in dementia

The failure of Alector Inc.’s phase III study of latozinemab in treating dementia halved the company’s stock on Oct. 22. That is also about the same percentage of staff that Alector is letting go after the clinical trial stumble. Read More
Arthritis pain illustration

Elevara raises $70M for phase II trial of CDK4/6 inhibitor in RA

Newco Elevara Medicines Ltd. has raised $70 million in a series A to fund a phase IIa/IIb trial of ELV-001, a first-in-class, oral cyclin dependent kinase 4/6 inhibitor, in the treatment of rheumatoid arthritis (RA) patients who do not have an adequate response to methotrexate and anti-TNF biologic therapies. Read More
Drug R&D concept image.

Flagship Pioneering launches Expedition to advance covalent-binding drugs

Expedition Medicines, which Flagship Pioneering Inc. has incubated for the past three years, came out of stealth mode with a $50 million commitment from Flagship to support Expedition’s platform technology to discover small molecules that covalently bind to their target. Read More
BioWorld-at-35.jpg

Celebrating BioWorld's 35th anniversary

From Dolly the sheep to mRNA vaccines, BioWorld has been reporting every breakthrough and challenge along the way. Our commitment to accurate, contextualized journalism has helped readers navigate this fast-evolving industry for 35 years. Join us as we celebrate the milestones that shaped biopharma and medtech, then and now. Read More

Appointments and advancements for Oct. 22, 2025

New hires and promotions in the biopharma industry, including: Biomatter, Brixton, Climb, Cytomx, Newleos, Synox, Talphera. Read More

Financings for Oct. 22, 2025

Biopharmas raising money in public or private financings, including: Atai, Chemify, Citius, Disc Medicine, Exeliom, Faeth, Lexeo, Minerva, Pleopharma, Xortx. Read More

In the clinic for Oct. 22, 2025

Clinical updates, including data readouts and publications: Advancell, Alto Neuroscience, Askbio, Bioinvent, Celcuity, Cidara, Faeth, Faron, GSK, Immatics, Incyte, Inovio, Neuphoria, Nxera, Rapt, Selection, Shanghai Jeyou, Spero, Springworks, Transgene. Read More

Other news to note for Oct. 22, 2025

Biopharma happenings, including deals and partnerships, and other news in brief: Arrowhead, Austrianova, Avant, CSL, Galapagos, Novartis, Pacira, Purdue, Roche, Teli, Telomir, Teva, Ventus. Read More

Regulatory actions for Oct. 22, 2025

Regulatory snapshots, including global drug submissions and approvals, and other regulatory decisions and designations: Bio Usawa, Cosmo, Gondolabio, GSK, Hoth, Immusoft, Quoin, Torii, Verrica. Read More

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