CureBeta, the diabetes research alliance between Evotec AG and Doug Melton's lab in Harvard University's Department of Stem Cell and Regenerative Biology, has found an early taker for its preclinical portfolio of small molecules and biologics that can trigger growth of insulin-secreting pancreatic beta cells. Read More
LONDON – The asthma treatment Flutiform finally won the seal of the European Commission recently, more than 12 years after SkyePharma plc set its sights on what it thought would be the relatively straightforward development of a combination product based on two marketed drugs. Read More
LONDON – A molecule that is needed for the proliferation and survival of malignant melanoma cells could hold clues to new therapies to treat that aggressive skin cancer. Read More
LONDON – PsiOxus Therapeutics Ltd. has raised £22 million (US$34 million) in its Series B round to finance the first clinical trial of its systemically acting oncolytic virus ColoAd1, in a 132-patient colorectal cancer study that will get under way in September. Read More
LONDON – Genkyotex SA has raised CHF25 million (US$26 million) as an extension to its Series C, with the existing investors all following on to fund Phase II development of the lead compound, GKT137831 in diabetic nephropathy. Read More
Opting for cash now rather than product sales later, Wilex AG decided to take a payment of $17.5 million as part of the deal it entered last year on the U.S. rights to its Phase III cancer antibody Rencarex (girentuximab) with Prometheus Laboratories Inc. It also stands to get another $2.5 million as part of a revised milestone payment that is contingent on a regulatory filing for the drug. Read More
• MDxHealth SA, of Liege, Belgium, said it expanded its collaboration with Merck KGaA, of Darmstadt, Germany, to cover the development and worldwide commercialization of MDxHealth's MGMT (methylguanine-DNA-methyltransferse) diagnostic test to identify glioblastoma patients who might be more likely to benefit from cilengitide, Merck's Phase III-stage integrin inhibitor. Read More
