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BioWorld Science

June 28, 2010

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GDNF gene therapy shows promise in Parkinson's disease model

RAD-1901 is efficacious in phase IIa trial in postmenopausal women

Novel RAF kinase inhibitors emerge from Takeda R&D

First-in-human data presented on MLN-9708 in nonhematologic cancer

Serotonin receptor modulators discovered at Nanotherapeutics

Concert Pharmaceuticals claims new deuterated agents

Kagawa Medical University claims new angiogenesis-promoting agents

GSK claims calcium-sensing CaS receptor ligands

Pardoprunox is effective in PD but dose adjustment is needed

Phase III data detailed for add-on safinamide in PD

Versartis commences phase Ia trial of VRS-859 in type 2 diabetes

Reduced melanoma cell growth observed in in vitro testing of GAP-107B8

AstraZeneca and Targacept begin phase III program for TC-5214 in MDD

Phase I trial of XMT-1107 initiated in patients with refractory advanced solid tumors

Infinity enrolling patients in phase I trial of IPI-493 for hematologic malignancies

First patients enrolled in phase I/II study of PVS-10200 for prevention of restenosis

Cellceutix's KM-391shown to increase serotonin levels in preclinical study

Sanofi-aventis begins phase I trial of anticancer agent SAR-650984

Amorfix and QED to co-develop high-affinity monoclonal antibodies for cancer

Anthera begins enrollment in pivotal phase III study of varespladib

EndoTAG-1 effective in triple receptor-negative breast cancer in phase II trial

Merck receives FDA approval for Dulera for asthma in patients 12 years and older

Santaris and miRagen develop microRNA-targeted cardiovascular medicines

FDA advisory committee meeting scheduled to review Contrave NDA

Sanofi-aventis and Metabolex enter into licensing agreement for novel antidiabetic

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