Home » Newsletters » BioWorld Science

BioWorld Science

June 1, 2021

View Archived Issues

Bacteriophage delivery of TNF-alpha gene therapy suppresses chondrosarcoma tumors in vivo

Merck & Co.'s [11C]L-235 can be used to assess target engagement of cathepsin K inhibitors

AbbVie initiates first-in-human study of ABBV-623 and ABBV-992

Nanjing Ruijie Pharma divulges ACC inhibitors

Nerviano Medical Sciences patents IDH inhibitors

Bayer presents new alpha2C-adrenoceptor antagonists

Jiangsu Simcere Pharmaceutical identifies new PRMT5 inhibitors

Shanghai SIMR Biotech synthesizes new PLA2G7 inhibitors

Phase I data for anti-PCSK9 peptide vaccine candidates AT-04A and AT-06A

Second cohort data from phase I/II study of NOX-A12 in glioblastoma multiforme

GPR55 promotes NASH development through ACC activation

EC-11770 shows broad-spectrum activity in nontuberculous mycobacterial infection models

Inflammation, depression share "core biological process"

SPK-10000, a liver-targeted gene therapy for the treatment of hereditary angioedema

Preclinical data show antiviral and anti-inflammatory activity of balixafortide in COVID-19

AB Science suspends inclusion in masitinib trials

Phase IIb study of vamorolone in Duchenne muscular dystrophy meets primary endpoint

FDA clears IND for anti-CD73 antibody HLX-23 for advanced solid tumors

Pivotal study of venglustat in ADPKD stopped for futility

CARB-X supports BioVersys' development of pyrrolocytosines targeting antibiotic-resistant bacteria

Neuren holds pre-IND meetings for phase II trials of NNZ-2591 for neurological disorders

Popular Stories

Today's news in brief
BioWorld
BioWorld briefs for Feb. 2, 2025.
Today's news in brief
Briefs
BioWorld MedTech briefs for Jan. 30, 2026.
Centessa’s CNT-9982 shows promise for MDD
BioWorld Science
Orexin OX2 receptor agonists have demonstrated the ability to enhance wakefulness in rodent models, as well as in nonhuman primates and patients with narcolepsy...
First-in-class ADC targeting DEM-TXX shows high preclinical efficacy
BioWorld Science
Researchers at DEM Biopharma Inc. reported preclinical findings demonstrating the efficacy of DEM-301, a bifunctional antibody-drug conjugate (ADC) engineered to...
5-HT2R allosteric ligands attenuate cocaine use and seeking behavior
BioWorld Science
Serotonergic G-protein-coupled receptors (GPCRs), including the 5-HT2A receptor (5-HT2AR) and 5-HT2CR, are key regulators of cortical signaling pathways and...