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BioWorld Science

June 1, 2021

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Bacteriophage delivery of TNF-alpha gene therapy suppresses chondrosarcoma tumors in vivo

Merck & Co.'s [11C]L-235 can be used to assess target engagement of cathepsin K inhibitors

AbbVie initiates first-in-human study of ABBV-623 and ABBV-992

Nanjing Ruijie Pharma divulges ACC inhibitors

Nerviano Medical Sciences patents IDH inhibitors

Bayer presents new alpha2C-adrenoceptor antagonists

Jiangsu Simcere Pharmaceutical identifies new PRMT5 inhibitors

Shanghai SIMR Biotech synthesizes new PLA2G7 inhibitors

Phase I data for anti-PCSK9 peptide vaccine candidates AT-04A and AT-06A

Second cohort data from phase I/II study of NOX-A12 in glioblastoma multiforme

GPR55 promotes NASH development through ACC activation

EC-11770 shows broad-spectrum activity in nontuberculous mycobacterial infection models

Inflammation, depression share "core biological process"

SPK-10000, a liver-targeted gene therapy for the treatment of hereditary angioedema

Preclinical data show antiviral and anti-inflammatory activity of balixafortide in COVID-19

AB Science suspends inclusion in masitinib trials

Phase IIb study of vamorolone in Duchenne muscular dystrophy meets primary endpoint

FDA clears IND for anti-CD73 antibody HLX-23 for advanced solid tumors

Pivotal study of venglustat in ADPKD stopped for futility

CARB-X supports BioVersys' development of pyrrolocytosines targeting antibiotic-resistant bacteria

Neuren holds pre-IND meetings for phase II trials of NNZ-2591 for neurological disorders

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