The good news is that BACE-1 inhibitors hit their targets. In that sense, in fact, the class has been "incredibly successful," Bruce Albala, executive director of neuroscience clinical development in Eisai Inc.'s neurology business group, told the audience at a symposium titled "Is BACE1 a suitable drug target for prevention and treatment of Alzheimer's disease?" at the 2018 Clinical Trials in Alzheimer's Disease (CTAD) meeting.