Biotech Co.*
(Country/
Symbol)

Pharma Co. (Country)

Product

Disclosed Funding (M)

Terms/Details (Date)


Aclara Bio-
Sciences Inc.
(ACLA)

Roche Applied
Science (unit
of Roche
Diagnostics)

Arteas product
line

ND

Collaboration for the worldwide marketing and distribution of Aclara's Arteas product line (11/7)

Alkermes
Inc.
(ALKS)

Janssen
Pharmaceutica
Products LP
(unit of Johnson
& Johnson)

Risperdal

ND

Agreement provides for the expansion of Alkermes' manufacturing capacity for production of Risperdal (10/30)

Applied
Gene Tech- nologies Inc.*

AsiaGen
(Taiwan)

Tuberculosis diagnostics

ND

Manufacturing and marketing agreement for tuberculosis diagnostics using Applied Gene's Tessera Array Technology; Applied Gene will receive an up-front payment for the development; AsiaGen gains exclusive rights to market and manufacture the product in Asia (11/5)

Bresagen
Ltd.
(Australia;
BSGNY)

ProGen
Industries Ltd.
(Australia)

Bacteria containing equine growth hormone, somatotropin

ND

Manufacturing supply agreement to produce the bacteria that produces the hormone, which will be purified by BresaGen and formulated into EquiGen (9/26)

Bresagen
Ltd.
(Australia;
BSGNY)

Image-Guided
Neurologics
Inc.

Specialized catheter intended to be used for delivery of cells into the brain

ND

IGN will develop the catheter for BresaGen, which has an exclusive license to commercialize the device (9/26)

Cell Thera-
peutics Inc.
(CTIC)

Natural Pharm-
aceuticals Inc.

Paclitaxel

ND

Supply agreement under which NPI will supply paclitaxel to CTI (10/23)

Connetics
Corp.
(CNCT)

Miza Pharma-
ceuticals Inc.
(Canada)

Luxiq and Olux foams

ND

Manufacturing and supply agreement for Luxiq and Olux targeted for the dermatology market; the agreement is for several years with a potential for renewal (9/21)

Dendreon
Corp.
(DNDN)

Gambro
Healthcare
Inc.

Dendreon's therapeutic
vaccines

ND

Gambro's U.S. network of clinics will serve as cell collection centers, and Gambro BCT's COBE Spectra Apheresis System will be used for the cell collection procedure; the collected cells serve as a raw material component in the production of Dendreon's cancer vaccines (10/23)

Dragon
Pharmaceu-
ticals
Inc.
(Canada; OTC
BB:DRUG)

Emcure
Pharmaceu-
ticals Ltd. (India)

Recombinant erythropoietin

ND

Marketing and licensing agreement for the distribution of the drug in India and and throughout the South Asian subcontinent, as well as in markets in sub-Saharan Africa (11/5)

Forest Lab-
oratories
Inc.
(NYSE:FRX)

Lipha SA
(subsidiary
of Merck
KGaA;
Germany)

Campral (acamprosate)

ND

Distribution, marketing, trademark license and supply agreement for the U.S. rights to Campral to treat alcohol addiction (10/23)

Genencor
International
Inc.
(GCOR)

The Procter
& Gamble Co.

Protease enzymes

$600

Five-year worldwide supply contract to provide protease enzymes for laundry and dish detergents; the agreement is estimated to be worth up to $600M in product revenues over the life of the contract (11/7)

InforMax
Inc.
(INMX)

Amersham
Biosciences
(unit of
Amersham
plc; UK)

InforMax desktop software products

ND

Agreement for the exclusive distribution of the products in Latin America (10/26)

Interneuron
Pharmaceu-
ticals
Inc.
(IPIC)

J. Uriach
& Cia. SA
(Spain)

Dersalazine, a compound to treat inflammatory bowel disease

ND

Interneuron gains worldwide marketing rights to dersalazine, except in Spain; it will be responsible for clinical development, regulatory activities and commercialization; the agreement includes an up-front licensing payment, development milestones and royalty payments to Uriach (10/1)

Lorus Thera-
peutics
Inc.
(Canada; OTC
BB:LORFF;
TSE:LOR)

Faulding
(Canada) Inc.

Virulizin

ND

Seven-year distribution agreement in which Faulding will market and sell Virulizin, to treat malignant melanoma, in Mexico; Lorus will receive royalties and will be responsible for manufacturing; Faulding will share in any additional clinical costs (10/15)

Myriad
Genetics
Inc.
(MYGN)

Fleury Lab-
oratories
(Brazil)

BRACAnalysis, Colaris and Myriad's new Melaris predictive medicine products

ND

Collaboration is to market the products throughout Brazil (11/14)

Orchid Bio-
sciences Inc.
(ORCH)

MiraiBio
Inc.

SNPstream MT

ND

Multiyear marketing agreement for Orchid's SNPstream MT product; MiraiBio gained nonexclusive worldwide rights to market the genotyping consumables and software developed by Orchid; Orchid retains rights to distribute the system (10/8)

Proteome
Systems Ltd.
(Australia)*

Alpha
Innotech
Corp.

Alphalmager and FluorChem imaging systems

ND

Alpha Innotech will manufacture the imaging systems for incorporation with Proteome Systems' ProteomeIQ integrated proteomics platform (10/15)

Third Wave
Technologies
Inc.
(TWTI)

Otsuka
Pharmaceu-
tical Co. Ltd.
(Japan)

Invader research products

ND

Marketing and distribution agreement under which Otsuka will distribute Invader research products in Japan and other countries in the Far East, Southeast Asia and the Middle East; Otsuka also will market and develop the product, as well as provide technical support (10/22)

Viragen Inc.
(AMEX:VRA)

Tradeway
Inc.

Multiferon

$255

Tradeway will purchase $5M of Viragen's natural alpha interferon product to complete the regulatory process in Taiwan; upon approval, Tradeway will purchase an additional $250M of the drug in increments of $50M over a five-year period (10/31)

Visible
Genetics
Inc.
(Canada;
VGIN)

Bio-
Reference
Laboratories
Inc. (BRLI)

TruGene HIV-1 Genotyping Test

ND

Agreement is to offer VGI's test to Bio-Reference customers treating patients with HIV infections; the companies will co-market and support the product in New York, New Jersey and greater Philadelphia, and provide patient education programs (9/25)


NOTES

# The information in the chart does not cover agricultural agreements or those between biotech companies.

* Private companies are indicated with an asterisk; unless otherwise noted, stock symbols listed are on the Nasdaq market.

** Denotes the date the item ran in BioWorld International.

ND = Not disclosed, reported and/or available

AMEX = American Stock Exchange; NYSE = New York Stock Exchange; OTC BB = Over the Counter Bulletin Board; TSE = Toronto Stock Exchange