I. FINANCING OF PRIVATE BIOTECHNOLOGY COMPANIES: $279.69M

Company

Location

Date

Amt. (M)

Details


AM Pharma BV

Bilthoven, the Netherlands

8/15**

EUR0.64 (US$0.59)

AM Pharma raised US$590,000 in its first round of funding; investors included AM Pharma's management, private investors and BioPartner Startup Ventures

Ark Therapeutics Ltd.

London

8/29**

#14.5 (US$21)

Ark raised US$21M in its third financing round led by BankInvest; other investors were Merlin Biosciences, Nomura International, Biofund and TVM

Automated Cell Inc.

Pittsburgh

8/6

$2.6

Automated Cell raised $2.6M from private and institutional investors

Cerylid Biosciences
Ltd.

Melbourne, Australia

8/23

$9.9

Cerylid raised $9.9M through an investment through JBWere Private Equity Fund, Rothschild BioScience Managers and CM Capital Investments

Chimeric Therapies Inc.

Laguna Niguel, Calif.

8/8

$9.7

Chimeric raised $9.7M in a venture financing; investors included Domain Associates, Alloy Ventures, 3i Biosciences, Sofinnova Ventures, Leeway & Co., Alafi Capital and Ell & Co.

Eyetech
Pharmaceuticals
Inc.

New York

8/9

$108.5

Eyetech closed its Series C round, raising $108.5 million; the round was led by J.P. Morgan Partners LLC; other investors were partners and affiliates of BB Biotech AG, MPM Capital, Alta Partners, Schroder Ventures and Merrill Lynch

Ionix
Pharmaceuticals
Ltd.

Cambridge,
UK

8/8**

#8
(US$11.4)

Ionix raised US$11.4M in its first funding led by Apax Partners and the Wellcome Trust

LaunchCyte
LLC

Pittsburgh

8/8

$0.7

LaunchCyte closed on $700,000 of interim financing; the funds were raised in a convertible debt offering

MBT Munich
Biotechnology
GmbH

Munich, Germany

8/21

EUR30.3
(US$27.8)

MBT completed the self-managed private placement led by Heidelberg Innovation; other investors were Deutsche Bank, Sal. Oppenheim, Deutsche Effecten, Hypo-Vereinsbank and Global Vision, as well as 3i, tbg and Global Life Science

Morphotek Inc.

Philadelphia

8/13

$10

Morphotek raised $10M in its second round of financing led by Applied Genomic Technology Capital Funds; other investors were Burrill & Co., CB Healthcare Ventures, Tonbridge Capital and Trieste Investment Group

Myogen Inc.

Denver

8/27

$52

Myogen completed its Series D financing round, raising $52.4M; the round was led by J.P. Morgan Partners; other investors were New Enterprise Associates, InterWest Partners, Adams Street Partners, Pacific Rim Ventures, Sequel Ltd. Partnership, CMEA Ventures and Montagu NewHall Associates

Q3DM Inc.

San Diego

8/22

$1.5

Q3DM raised $1.5M in its Series A round led by Aztec Venture Network LLC and California Tech Coast Angel

TaiGen
Biotechnology
Co.

Taiwan

8/20

$24

TaiGen raised $24M in the first half of a Series A financing; MPM led the financing, and was joined by various Chinese investors (8/20)

II. MILESTONE PAYMENTS AND EQUITY INVESTMENTS FROM EXISTING CORPORATE PARTNERS: $21.6M

Company
(Symbol)#*

Partner
(Country)

Amt.
(M)

Triggering
Event

Details (Date)


Alliance
Pharmaceutical
Corp.
(ALLP)

Baxter Healthcare Corp.

$4

Investment

Baxter made a $4M investment in Alliance Series F preferred stock (8/2)

Collateral
Therapeutics
Inc.
(CLTX)

Schering AG
(Germany)

$4

Milestone payment

Collateral received a $4M payment from Schering for the clinical advancement of Generx and Genvascor (8/13)

Cytoclonal
Pharmaceutics
Inc.
(CYPH)

Bristol-Myers Squibb Co.

$0.6

Milestone payment

Cytoclonal received payments totaling more than $600,000 for its work on Taxol-related projects (8/15)

Discovery
Genomics Inc.*

Techne Corp.

$3

Investment

Techne made a $3M investment in Discovery Genomics as part of a research and license agreement to develop antibodies and immunoassays and to sell the products (8/9)

Exelixis Inc.
(EXEL)

Bayer AG (Germany)

ND

Milestone payment

Exelixis achieved additional milestones through the delivery of assays (8/30)

Organogenesis
Inc.
(AMEX:
ORG)

Novartis
Pharma AG (Switzerland)

$10

Equity investment

Organogenesis is selling $10M in equity to Novartis as part of an agreement made earlier in the year (8/7)

Paradigm
Genetics Inc.
(PDGM)

Bayer AG (Germany)

ND

Milestone payment

Bayer installed new assays for screening in its ultra-high-throughput facility; the delivery of the assays triggered milestone payments to Paradigm (8/6)

Quark Biotech
Inc.*

Taisho
Pharmaceutical Co. Ltd. (Japan)

ND

Equity investment

Taisho made an equity investment in Quark as part of a Series F financing (8/22)

TransTech
Pharma Inc.*

Novo Nordisk A/S (Denmark)

ND

Equity investment

Novo Nordisk made an undisclosed equity investment in TransTech as part of a collaboration to generate clinical candidates from Novo's targets (8/15)


Notes:

# Unless otherwise indicated, shares are traded on the Nasdaq exchange.

* Denotes privately held company.

** Denotes the date the item ran in BioWorld International.

ND = Not disclosed

NDA = New Drug Application

AMEX = American Stock Exchange