Biotech Co.* (Symbol)

Pharma Co. (Country)

Product

Disclosed Funding (M)

Terms/Details (Date)

Acambis plc (UK; ACAM; LSE:ACM)

Swiss Serum and Vaccine Institute Berne (Switzerland)

Oral typhoid vaccine

ND

Swiss Serum will fund all process development and supply of clinical trial materials and will manufacture the vaccine and supply it to Acambis; the companies will share the costs of the remaining trials of the vaccine; Acambis gains exclusive sales and marketing rights in the U.S. and Canada to sell an oral cholera vaccine, Orochol Berna, in combination with its oral typhoid vaccine (3/16)

Applera Corp.(consists of two units: Applied Biosystems, NYSE:ABI; and Celera Genomics, NYSE:CRA)

Pantheco A/S (Denmark)

Peptide nucleic acids

ND

Applera's subsidiary Applied Biosystems Group acquired a small minority stake in Pantheco; agreement includes a nonexclusive license agreement to manufacture peptide nucleic acids for research and development purposes (3/7**)

Biotech Holdings Ltd. (Canada; OTC BB:BIOHF)

Bilim Pharmaceuticals Inc. (Turkey)

DIAB II

ND

Bilim will distribute DIAB II in Turkey (3/27)

Durect Corp. (DRRX)

Mallinckrodt Inc.

Sufentanil

ND

Durect recently completed patient enrollment for a Phase II trial of Duros sufentanil; Mallinckrodt will supply sufentanil to treat chronic pain (3/27)

Lorus Therapeutics Inc. (Canada; LORFF; TSE:LOR)

Dalton Chemical Laboratories Inc. (Canada)

Virulizin

ND

The agreement will provide supply for the Phase III trial and prepare for potential commercial sales (3/12)

MGI Pharma Inc. (MOGN)

Helsinn Healthcare SA (Switzerland)

Palonosetron

$11

The deal includes $11M in up-front payments and grants MGI exclusive North American license and distribution rights (4/10)

Pharsight Corp. (PHST)

iBiomatics LLC

Pharsight's Computer-Assisted Trial Design methodology

ND

iBiomatics will market the Pharsight Trial Simulator and iBiomatics' webbased platform for biomedical informatics (3/8)

Vysis Inc. (VYSI)

Abbott Laboratories Inc.

Genomic tests related to breast and bladder cancer

ND

Abbott gets exclusive distribution rights in North America and Europe for the PathVysion HER-2 assay and the UroVysion assay (4/5)

Xanthon Inc.*

CMED/RELA (division of Colorado MEDtech Inc.)

Xanthon Xpression Analysis Instrument

ND

Xanthon will begin receiving instruments in anticipation of a product launch in 2002; agreement is for the manufacturing for production quantities of the Xanthon Xpression Analysis Instrument (3/12)

NOTES

# The information in the chart does not cover agreements between biotech companies or agricultural agreements.

* Private companies are indicated with an asterisk; unless otherwise noted, stock symbols listed are on the NASDAQ market.

** Denotes the date the item ran in BioWorld International.

ND = Not disclosed, reported and/or available

LSE = London Stock Exchange; NYSE = New York Stock Exchange; OTC BB = Over the Counter Bulletin Board; TSE = Toronto Stock Exchange