BioWorld Stock Report For Public Biotechnology Companies Part 2 Company Symbol Close Close Close Close % Chg 12/31* 3/31 6/30 9/30 YTDIBAH IBAH 6.750 6.375 3.562 4.750 -30ICN Pharma. ICN 19.625 22.250 28.687 49.187 151Icos ICOS 7.625 7.312 8.250 12.625 66ID Biomed IDB* 5.750 4.900 5.200 4.150 -28IDEC Pharm IDPH 23.750 23.812 24.250 41.875 76Idexx Labs IDXX 36.000 14.000 12.437 16.750 -53Igen IGEN 5.000 5.250 7.500 13.500 170ILEX Oncology ILXO 12.000 12.125 15.875 12.000 0ImClone Sys IMCL 9.750 5.750 6.125 8.125 -17Immucell ICCC 2.375 2.250 2.750 2.562 8Immucor BLUD 9.750 9.500 9.875 10.250 5ImmuLogic IMUL 6.375 4.375 3.125 3.312 -48Immune Resp IMNR 8.250 8.375 7.625 12.625 53Immunex IMNX 19.500 26.500 36.250 67.250 245ImmunoGen IMGN 2.375 1.375 1.562 1.250 -47Immunomed IMMU 5.500 4.625 4.375 4.687 -15Incyte Pharm INCY 51.500 52.000 67.000 84.000 63Inhale Ther Sys INHL 15.125 19.125 24.750 31.375 107Innovir INVR 1.187 0.750 1.093 0.875 -26InSite Vision INSV 6.000 4.312 5.500 4.625 -23Integra LifeScien IART 4.625 3.812 3.125 4.187 -9Intercardia ITRC 21.500 22.250 23.000 22.500 5Interferon Sci IFSC 6.625 6.250 9.000 8.625 30Interneuron IPIC 26.000 17.625 20.125 12.000 -54Intl Murex MURXF 7.312 6.937 8.562 9.500 30Isis Pharm ISIP 18.000 15.000 14.562 17.812 -1La Jolla Pharm LJPC 6.000 5.000 4.625 5.000 -17LeukoSite (6) LKST 6.000 9.875 65Lidak Pharm LDAKA 1.750 2.375 2.187 2.468 41Life Tech LTEK 25.000 26.250 27.750 30.250 21Lifecell LIFC 3.125 6.500 5.875 7.875 152Lifecore Bio LCBM 18.000 14.875 13.750 18.000 0Ligand LGND 14.875 11.250 12.875 16.500 11Liposome Co LIPO 19.125 20.375 8.937 6.937 -64LXR Biotech LXR 2.250 2.187 2.375 1.937 -14MacroChem MCHM 6.500 4.937 6.812 8.750 35Magainin MAGN 9.625 8.500 7.250 11.437 19Martek Bio MATK 20.000 17.500 11.750 15.000 -25Matritech NMPS 8.500 5.062 6.937 5.562 -35Matrix MATX 6.125 6.375 6.687 4.937 -19Maxim Pharma MMP 7.000 9.000 9.750 15.500 121Medarex MEDX 7.000 7.250 6.312 6.437 -8MedImmune MEDI 17.000 13.750 18.500 36.750 116Megabios (7) MBIO 12.000 16.750 40Meridian Diag KITS 13.000 11.000 8.375 11.875 -9Metra Biosys MTRA 4.750 4.250 4.812 3.500 -26Microcide Pharma MCDE 10.000 12.500 11.000 12.500 25Micrologix Biotec MBI* 3.600 4.250 4.270 5.000 39Millennium MLNM 17.375 13.625 16.125 19.500 12Molec Dynam MDYN 10.750 14.750 14.000 27.000 151Molecular Bio MB 6.500 9.125 9.000 11.625 79Molecular Devices MDCC 15.562 13.875 17.500 21.875 41Mycogen MYCO 21.500 23.250 19.625 23.500 9Myriad Genetics MYGN 25.250 34.500 27.000 25.937 3NABI NABI 8.750 6.812 6.625 7.312 -16NaPro Biother NPRO 11.000 13.000 7.250 8.625 -22NeoPharm NEO 8.000 7.625 4.875 5.000 -38Neoprobe NEOP 15.375 13.500 14.000 14.000 -9NeoRx Corp. NERX 4.125 4.937 4.437 7.000 70Neose Technol NTEC 18.000 13.750 12.750 18.000 0NeoTherapeutics NEOT 4.125 5.437 15.875 14.125 242Neurex NXCO 17.000 11.875 14.125 14.750 -13Neurobio Tech NTII 3.750 1.750 2.250 3.250 -13Neurocrine Biosci NBIX 10.000 9.000 9.000 9.562 -4Neurogen NRGN 19.250 19.000 22.750 27.000 40NeXstar Pharm NXTR 15.000 10.000 14.250 17.750 18North Am Vacc NVX 24.375 20.125 19.312 25.250 4Northfield Labs NFLD 10.750 11.125 10.375 11.500 7Novavax NOX 3.437 3.375 4.125 5.437 58Noven NOVN 14.000 9.000 7.125 7.000 -50NPS Pharm NPSP 11.000 9.500 9.625 9.250 -16Oncogene Sci ONCS 6.375 6.375 5.375 10.875 71Oncor ONC 4.000 3.625 4.000 5.062 27OncorMed ONM 4.812 4.125 5.937 7.500 56Onyx Pharma ONXX 11.125 12.000 10.250 8.750 -21OraVax ORVX 5.250 2.750 2.750 2.750 -48Organogenesis ORG 22.625 17.750 19.687 29.250 29Ortec Int'l ORTC 10.375 8.625 9.000 13.750 33Osteotech OSTE 7.000 7.875 10.500 20.125 188Ostex Int'l OSTX 5.500 3.750 2.375 3.625 -34OXiGENE OXGN 23.500 32.000 34.750 27.250 16Oxis Int'l OXIS 1.250 0.968 0.687 0.625 -50Pacific Pharma (8) PHA 1.250 1.187 1.437 1.875 50Panax Pharma PANXU 0.625 3.250 2.031 1.750 180Paracelsian PRLN 1.625 1.250 0.500 0.437 -73Parexel Intl PRXL 25.813 23.000 31.750 39.500 53PathoGenesis PGNS 21.750 25.000 29.125 35.500 63Penederm DERM 12.375 11.000 13.500 13.625 10PerSeptive Bio PBIO 6.937 7.875 6.125 12.000 73Pharma Prod Devlp PPDI 25.250 20.000 22.000 20.375 -19Pharmacopeia PCOP 19.375 17.125 13.250 22.625 17Pharmacyclics PCYC 16.000 15.875 15.500 24.750 55Pharmos PARS 1.468 1.375 1.843 2.781 89Phoenix Intl PHX* 12.250 9.700 10.850 11.350 -7Procept PRCT 1.062 0.875 0.468 0.312 -71ProCyte PRCY 2.250 1.750 1.125 1.156 -49Progenitor (9) PGEN 5.375 4.625 -14Protein Design PDLI 36.500 30.000 28.500 38.750 6Protein Poly PPTI 2.562 3.062 2.250 2.687 5Qiagen QGENF 25.750 33.250 48.187 46.500 81QLT PhotoTher QLTIF 20.125 20.750 21.000 16.437 -18Quidel QDEL 4.500 3.875 3.250 4.937 10Quintiles QTRN 66.250 53.875 69.625 84.250 27Regeneron REGN 16.125 8.000 10.125 11.187 -31Repligen RGEN 1.187 1.468 1.187 1.156 -3Ribi Immuno RIBI 3.875 4.437 4.625 4.250 10Ribozyme Pharm RZYM 11.000 10.875 8.750 11.500 5SangStat Med SANG 26.500 27.125 23.125 30.625 16SciClone SCLN 8.000 6.562 5.125 5.625 -30Scios SCIO 6.140 6.812 6.375 9.750 59Sepracor SEPR 16.625 23.062 25.812 32.875 98Sequana Therap SQNA 16.750 12.750 10.875 13.750 -18Sequus Pharm SEQU 16.000 7.625 6.375 8.625 -46Shaman SHMN 5.875 5.125 5.937 6.750 15Sheffield SHM 3.750 2.750 2.937 2.437 -35SIBIA Neurosci SIBI 7.500 8.250 6.500 8.375 12Siga Pharma (10) SGPH 5.000 5.375 8Somatogen SMTG 11.000 6.125 4.625 6.937 -37Sonus Pharma SNUS 29.750 26.375 28.125 42.000 41Sparta Pharm SPTA 1.468 0.718 0.625 0.750 -49Sugen SUGN 12.875 10.500 12.875 20.125 56SunPharm SUNP 5.000 3.750 3.687 3.625 -28SuperGen SUPG 12.250 11.125 14.750 17.500 43Synaptic Pharma SNAP 12.000 14.000 13.125 13.500 13Synbiotics SBIO 3.187 3.875 4.125 3.875 22Synsorb Biotech SYB* 11.600 9.000 8.800 9.700 -16T Cell Sci TCEL 1.625 1.562 1.875 2.125 31Targeted Genet TGEN 4.500 3.500 2.750 5.437 21Techniclone Int'l TCLN 4.500 4.937 4.375 3.031 -33Teva Pharm TEVIY 50.250 55.500 64.750 55.750 11Texas Biotech TXB 4.375 4.500 4.875 5.750 31Therapeut Disc TDCA 11.125 11.000 11.125 12.187 10Theratech THRT 13.250 10.750 11.750 11.625 -12Titan Pharma TTNPU 12.875 4.125 3.562 5.500 -57Transcend Ther (11) TSND 10.000 8.500 -15Transkaryotic TKTX 18.500 19.500 30.875 39.250 112Trega Bioscien TRGA 5.250 5.750 6.125 4.125 -21Triangle Pharma VIRS 22.875 15.750 24.875 19.250 -16Trinity Bio TRIBY 2.343 2.500 2.562 2.750 17Tripos TRPS 11.750 15.250 15.625 19.000 62Unigene UGNE 2.031 3.375 4.750 3.812 88UroCor UCOR 9.562 9.250 9.375 8.750 -8US Bioscience UBS 12.625 11.625 9.625 11.375 -10Vertex Pharm VRTX 40.250 40.250 38.250 37.750 -6Vical VICL 16.500 14.500 12.750 14.125 -14VimRx VMRX 3.375 2.875 3.218 2.562 -24Vion Pharma VION 3.062 4.250 4.562 5.125 67Viragen VRGN 5.218 2.500 2.531 2.343 -55ViroPharma VPHM 8.750 13.000 17.875 22.000 151Virus Research VRII 5.750 8.250 6.750 6.500 13Visible Genetics VGINF 8.750 3.750 6.000 10.250 17Vyrex VYRX 12.750 6.000 6.078 7.375 -42Xenova Group XNVAY 3.250 5.687 5.250 4.000 23XOMA XOMA 5.125 5.500 4.812 7.750 51Zonagen ZONA 9.375 16.125 21.875 36.000 284NOTES:1. Agouron Pharmaceuticals Inc. (NASDAQ:AGPH) split its stock 2 for 1, effective 8/29/97. The historical prices have been adjusted accordingly.2. BioChem Pharma Inc. changed its NASDAQ symbol from BCHXF to BCHE, effective 7/10/97.3. Bioreliance Corp. (NASDAQ:BREL) completed its IPO 7/28/97. The stock was priced at $15.00 per share.4. DeKalb Genetics Corp. (NYSE:DKB) split its stock 2 for 1, effective 8/8/97. The historical prices have been adjusted accordingly.5. Hyseq Inc. (NASDAQ:HYSQ) completed its IPO 8/7/97. The stock was priced at $14.00 per share.6. LeukoSite Inc. (NASDAQ:LKST) completed its IPO 8/15/97. The stock was priced at $6.00 per share.7. Megabios Corp. (NASDAQ:MBIO) completed its IPO 9/15/97. The stock was priced at $12.00 per share.8. Xytronyx Inc. (AMEX:XYX) has changed its company name to Pacific Pharmaceuticals Inc. and its AMEX trading symbol to PHA, effective 8/14/97. 9. Progenitor Inc. (NASDAQ:PGEN) completed its IPO 8/7/97. The stock was priced at $7.00 per unit (the unit share price was $5.375).10. Siga Pharmaceuticals Inc. (NASDAQ:SGPH) completed its IPO 9/9/97. The stock was priced at $5.00 per share.11. Transcend Therapeutics Inc. (NASDAQ:TSND) completed its IPO 7/2/97. The stock was priced at $10.00 per share.* The prices listed in the 12/31/96 column represent the 1996 closing prices or, for those stocks that started trading in 1997, the IPO prices. There are 298 stocks on this list; the average percent change year-to-date (YTD) is +13.95%.