| Company | Symbol | Close | Close | Close | Close | % Chg | ||
| 12/31* | 3/31 | 6/30 | 9/30 | YTD | ||||
| Aastrom Biosci | ASTM | 7.000 | 5.750 | 7.125 | 7.687 | 10 | ||
| AccuMed Intl | ACMI | 2.500 | 3.625 | 3.562 | 2.906 | 16 | ||
| Adv Magnetics | AVM | 15.500 | 13.500 | 10.875 | 10.687 | -31 | ||
| Adv Poly Sys | APOS | 7.625 | 7.750 | 8.000 | 7.750 | 2 | ||
| Adv Tissue Sci | ATIS | 9.562 | 10.500 | 12.875 | 15.562 | 63 | ||
| Affymetrix | AFFX | 20.187 | 27.000 | 34.750 | 46.000 | 128 | ||
| Agouron (1) | AGPH | 33.875 | 35.313 | 40.438 | 48.125 | 42 | ||
| Alexion Pharma | ALXN | 8.687 | 10.375 | 8.875 | 14.750 | 70 | ||
| Alkermes | ALKS | 23.250 | 14.000 | 14.500 | 20.625 | -11 | ||
| Allelix | AXB* | 16.800 | 11.550 | 10.800 | 14.250 | -15 | ||
| Alliance | ALLP | 13.625 | 12.125 | 10.062 | 11.937 | -12 | ||
| Alpha Beta | ABTI | 10.562 | 10.625 | 9.125 | 2.968 | -72 | ||
| ALRT | ALRI | 19.000 | -- | 17.250 | 21.250 | 12 | ||
| AltaRex | AXO* | 6.297 | 5.350 | 3.500 | 3.500 | -44 | ||
| Alteon | ALTN | 5.250 | 3.312 | 4.218 | 5.312 | 1 | ||
| Alza | AZA | 25.875 | 27.500 | 29.000 | 29.000 | 12 | ||
| Am Bio Sci | MABXA | 4.062 | 3.562 | 3.187 | 3.687 | -9 | ||
| Amarillo Biosci | AMAR | 4.750 | 3.750 | 3.625 | 3.750 | -21 | ||
| AMBI Inc. | AMBI | 2.875 | 2.875 | 2.375 | 2.500 | -13 | ||
| Amgen | AMGN | 54.375 | 55.875 | 58.125 | 47.937 | -12 | ||
| Amylin | AMLN | 13.000 | 12.125 | 13.750 | 8.437 | -35 | ||
| Anergen | ANRG | 3.750 | 3.625 | 3.062 | 3.250 | -13 | ||
| Anesta | NSTA | 19.250 | 17.250 | 19.000 | 23.250 | 21 | ||
| Ansan | ANSNU | 4.968 | 4.718 | 3.000 | 2.500 | -50 | ||
| AntiVirals | AVII | 6.500 | -- | 7.125 | 7.187 | 11 | ||
| Aphton | APHT | 19.500 | 14.000 | 14.750 | 13.750 | -29 | ||
| Aquila Biophar | AQLA | 4.875 | 5.000 | 5.687 | 5.062 | 4 | ||
| Ariad Pharm | ARIA | 5.062 | 6.062 | 6.437 | 5.875 | 16 | ||
| Aronex Pharma | ARNX | 9.375 | 5.750 | 3.875 | 6.500 | -31 | ||
| ArQule | ARQL | 15.750 | 15.500 | 17.375 | 21.000 | 33 | ||
| Arris Pharm | ARRS | 13.500 | 12.250 | 13.250 | 13.000 | -4 | ||
| Atlantic Pharma | ATLC | 6.125 | 5.813 | 7.000 | 8.000 | 31 | ||
| Atrix Labs | ATRX | 10.750 | 10.875 | 12.250 | 19.500 | 81 | ||
| Aurora Bioscien | ABSC | 10.000 | -- | 10.375 | 14.312 | 43 | ||
| AutoImmune | AIMM | 15.375 | 11.000 | 1.843 | 2.812 | -82 | ||
| Avigen | AVGN | 5.000 | 4.250 | 3.500 | 4.000 | -20 | ||
| Aviron | AVIR | 7.500 | 9.500 | 12.250 | 25.125 | 235 | ||
| Axogen | AXG/U | 23.500 | 23.000 | 32.000 | 37.437 | 59 | ||
| Bio-Tech Gen | BTGC | 13.125 | 12.500 | 13.500 | 15.000 | 14 | ||
| Biochem Phar (2) | BCHE | 25.125 | 21.500 | 22.250 | 31.500 | 25 | ||
| Biocircuits | BIOC | 2.906 | 1.250 | 0.812 | 1.000 | -66 | ||
| BioCryst | BCRX | 16.375 | 11.875 | 13.750 | 8.000 | -51 | ||
| Biogen | BGEN | 38.750 | 37.375 | 33.875 | 32.437 | -16 | ||
| Bioject | BJCT | 0.687 | 0.781 | 0.687 | 1.000 | 46 | ||
| Biomatrix | BIOX | 16.000 | 13.375 | 19.000 | 35.125 | 120 | ||
| Biomira | BIOMF | 4.750 | 5.125 | 5.062 | 5.000 | 5 | ||
| Biomune Sys | BIME | 1.468 | 1.250 | 0.468 | 0.375 | -74 | ||
| Biora AB | BIORY | 16.500 | 20.000 | 17.875 | 18.750 | 14 | ||
| Bioreliance (3) | BREL | 15.000 | -- | -- | 26.250 | 75 | ||
| Biosys | BIOSQ | 0.065 | 0.010 | 0.010 | 0.010 | -85 | ||
| Biotime | BTIM | 28.000 | 31.250 | 33.000 | 51.000 | 82 | ||
| BioTransplant | BTRN | 6.500 | 6.875 | 6.750 | 5.625 | -13 | ||
| Boston Life | BLSI | 6.875 | 0.656 | 7.250 | 7.187 | 5 | ||
| British Biotech | BBIOY | 34.500 | 40.125 | 38.500 | 26.375 | -24 | ||
| Cadus Pharma | KDUS | 8.750 | 12.125 | 14.250 | 11.375 | 30 | ||
| Calypte Biomed | CALY | 8.250 | 6.875 | 4.500 | 7.000 | -15 | ||
| Cambridge Neuro | CNSI | 11.875 | 10.625 | 4.125 | 2.250 | -81 | ||
| Cantab Pharm | CNTBY | 9.500 | 16.750 | 14.000 | 13.500 | 42 | ||
| Carrington | CARN | 7.750 | 6.000 | 6.250 | 6.125 | -21 | ||
| Cel-Sci | HIV | 4.250 | 4.312 | 3.750 | 7.250 | 71 | ||
| Celgene | CELG | 11.125 | 7.125 | 7.375 | 11.125 | 0 | ||
| Cell Genesys | CEGE | 9.125 | 6.125 | 4.937 | 7.875 | -14 | ||
| Cell Therapeutics | CTIC | 10.000 | 10.000 | 11.125 | 14.875 | 49 | ||
| CellPro | CPRO | 12.500 | 6.437 | 6.000 | 4.687 | -63 | ||
| Celtrix | CTRX | 2.000 | 2.437 | 2.312 | 2.625 | 31 | ||
| Centocor | CNTO | 35.750 | 30.500 | 31.062 | 47.562 | 33 | ||
| Cephalon | CEPH | 20.500 | 21.000 | 11.500 | 11.750 | -43 | ||
| ChemTrak | CMTR | 1.343 | 1.718 | 1.187 | 0.687 | -49 | ||
| Chiron | CHIR | 18.625 | 18.625 | 20.875 | 22.625 | 21 | ||
| Cholestech | CTEC | 5.625 | 5.125 | 5.750 | 10.750 | 91 | ||
| Chrysalis Intl | CRLS | 4.375 | 5.125 | 4.250 | 4.000 | -9 | ||
| CIMA Labs | CIMA | 6.125 | 6.000 | 4.125 | 6.750 | 10 | ||
| ClinTrials | CCRO | 22.750 | 8.500 | 12.000 | 9.375 | -59 | ||
| CoCensys | COCN | 5.750 | 5.375 | 3.125 | 5.875 | 2 | ||
| Collab. Clin. Res | CCLR | 10.750 | 7.250 | 7.000 | 5.875 | -45 | ||
| CollaGenex | CGPI | 8.125 | 14.250 | 12.000 | 10.125 | 25 | ||
| Columbia Labs | COB | 14.500 | 12.250 | 16.375 | 19.000 | 31 | ||
| Connetics Corp | CNCT | 8.250 | 7.375 | 7.000 | 3.625 | -56 | ||
| Cor Thera | CORR | 9.875 | 9.500 | 10.625 | 16.625 | 68 | ||
| Cortech | CRTQ | 1.468 | 0.875 | 0.625 | 0.703 | -52 | ||
| Cortecs Intl | DLVRY | 14.500 | 20.875 | 16.250 | 15.875 | 9 | ||
| Cortex | CORX | 3.687 | 2.875 | 3.125 | 2.968 | -20 | ||
| Corvas | CVAS | 5.625 | 5.500 | 6.500 | 5.125 | -9 | ||
| Coulter Pharma | CLTR | 12.000 | 9.125 | 9.750 | 13.375 | 11 | ||
| Creative Bio | CBMI | 10.375 | 7.500 | 7.062 | 10.750 | 4 | ||
| Cubist Pharma | CBST | 6.125 | 10.500 | 6.500 | 5.875 | -4 | ||
| CV Therapeutics | CVTX | 6.500 | 8.750 | 7.500 | 9.500 | 46 | ||
| Cyanotech | CYAN | 6.437 | 5.562 | 4.937 | 5.750 | -11 | ||
| Cygnus | CYGN | 14.500 | 13.625 | 17.250 | 19.750 | 36 | ||
| Cypress Bio | CYPB | 1.937 | 1.687 | 2.125 | 1.968 | 2 | ||
| Cypros Pharma | CYPR | 3.937 | 5.312 | 4.500 | 4.187 | 6 | ||
| Cytel | CYTL | 3.437 | 2.375 | 1.625 | 2.375 | -31 | ||
| Cytoclonal Phar | CYPH | 2.125 | 3.250 | 2.625 | 7.375 | 247 | ||
| Cytogen | CYTO | 5.500 | 5.812 | 4.875 | 3.937 | -28 | ||
| CytoTherapeut | CTII | 9.000 | 8.125 | 5.375 | 5.500 | -39 | ||
| CytRx | CYTR | 3.437 | 3.687 | 3.750 | 4.875 | 42 | ||
| Dekalb (4) | DKB | 25.500 | 26.625 | 39.875 | 44.375 | 74 | ||
| DepoTech | DEPO | 16.375 | 15.250 | 13.625 | 13.500 | -18 | ||
| Diacrin | DCRN | 10.250 | 13.250 | 11.000 | 11.250 | 10 | ||
| Diagnostic Prod | DP | 25.875 | 29.875 | 31.562 | 30.187 | 17 | ||
| Dianon Systems | DIAN | 8.625 | 8.625 | 9.625 | 8.500 | -1 | ||
| Diatide | DITI | 7.125 | 6.250 | 5.250 | 12.000 | 68 | ||
| Digene | DIGE | 10.500 | 11.375 | 12.750 | 12.875 | 23 | ||
| DNAP Holding | DNAP | 3.500 | 4.250 | 3.500 | 5.000 | 43 | ||
| Draxis Health | DRAXF | 2.187 | 2.406 | 2.375 | 2.812 | 29 | ||
| Dura Pharm | DURA | 47.750 | 35.750 | 39.875 | 43.625 | -9 | ||
| DynaGen | DYGN | 1.312 | 1.437 | 1.000 | 0.562 | -57 | ||
| Ecogen | EECN | 2.500 | 3.562 | 3.500 | 3.125 | 25 | ||
| Elan | ELN | 33.250 | 34.125 | 45.250 | 50.062 | 51 | ||
| Embrex | EMBX | 6.500 | 6.875 | 7.000 | 6.562 | 1 | ||
| Emisphere | EMIS | 18.625 | 16.250 | 22.250 | 22.000 | 18 | ||
| Endorex | ENDR | 14.063 | 7.969 | 2.625 | 2.625 | -81 | ||
| EntreMed | ENMD | 16.250 | 12.750 | 12.000 | 9.937 | -39 | ||
| Envirogen | ENVG | 3.375 | 2.562 | 2.937 | 3.250 | -4 | ||
| Enzo Biochem | ENZ | 18.125 | 13.750 | 15.812 | 18.000 | -1 | ||
| Enzon | ENZN | 2.937 | 2.562 | 2.250 | 4.875 | 66 | ||
| Epitope | EPTO | 11.500 | 10.500 | 7.875 | 8.250 | -28 | ||
| Epix Medical | EPIX | 7.000 | 6.625 | 8.000 | 12.000 | 71 | ||
| Ergo Science | ERGO | 13.125 | 11.375 | 11.000 | 13.250 | 1 | ||
| Ethical Hldgs | ETHCY | 5.812 | 5.000 | 4.437 | 4.562 | -22 | ||
| Flamel Tech | FLMLY | 7.500 | 6.625 | 4.562 | 4.000 | -47 | ||
| GalaGen | GGEN | 4.375 | 2.562 | 2.750 | 2.250 | -49 | ||
| GelTex | GELX | 24.250 | 21.250 | 20.125 | 26.750 | 10 | ||
| Genelabs | GNLB | 6.125 | 4.375 | 2.812 | 4.250 | -31 | ||
| GeneMedicine | GMED | 5.687 | 6.250 | 7.750 | 4.125 | -27 | ||
| Genentech | GNE | 53.625 | 57.125 | 58.937 | 58.125 | 8 | ||
| Genome Thera | GENE | 10.750 | 6.875 | 8.625 | 8.750 | -19 | ||
| Genset | GENXY | 16.000 | 15.875 | 19.375 | 21.125 | 32 | ||
| Gensia Sicor | GNSA | 4.625 | 3.937 | 4.437 | 6.937 | 50 | ||
| Genta | GNTA | 4.375 | 2.813 | 2.156 | 1.937 | -56 | ||
| Genz Tiss Repair | GENZL | 7.125 | 9.875 | 10.125 | 9.750 | 37 | ||
| Genzyme | GENZ | 21.750 | 22.500 | 27.750 | 29.750 | 37 | ||
| Genzyme Trans | GZTC | 6.125 | 8.125 | 8.500 | 11.500 | 88 | ||
| Geron | GERN | 13.250 | 9.750 | 7.500 | 10.875 | -18 | ||
| Gilead Sciences | GILD | 25.000 | 22.875 | 27.625 | 44.375 | 78 | ||
| Gliatech | GLIA | 7.750 | 10.125 | 8.250 | 11.750 | 52 | ||
| Guilford Pharm | GLFD | 23.250 | 20.750 | 24.250 | 29.500 | 27 | ||
| Hemacare | HEMA | 3.125 | 2.375 | 1.687 | 1.000 | -68 | ||
| HemaSure | HMSR | 6.250 | 4.000 | 2.750 | 3.875 | -38 | ||
| Human Genome | HGSI | 40.750 | 32.500 | 33.250 | 43.062 | 6 | ||
| Hybridon | HYBN | 5.875 | 6.500 | 5.000 | 1.937 | -67 | ||
| Hycor Bio | HYBD | 3.000 | 2.625 | 2.031 | 2.281 | -24 | ||
| Hyseq (5) | HYSQ | 14.000 | -- | -- | 19.875 | 42 | ||
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