YAP/TAZ-TEAD inhibitors described in joint Katholieke Universiteit Leuven and Springworks Therapeutics patent

Aug. 30, 2023

Katholieke Universiteit Leuven and Springworks Therapeutics Inc. have jointly identified tetrahydropyridopyrimidines acting as transcriptional coactivator YAP1/transcriptional enhancer factor (TEAD) or WW domain-containing transcription regulator protein 1 (WWTR1; TAZ)/TEAD interaction inhibitors.

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