Mindrank AI discovers new ALK mutant and ROS1 inhibitors

Oct. 20, 2023

Mindrank AI Co. Ltd. has described macroheterocyclic compounds acting as ALK mutant and ROS1 inhibitors reported to be useful for the treatment of cancer and immunological disorders.

BioWorld Science Cancer Patents

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BioWorld

BioWorld briefs for April 15, 2026.

MMP inhibitors divulged in Accure Therapeutics patent

BioWorld Science

Accure Therapeutics has reported new oligopeptide derivatives acting as matrix metalloproteinase-2 (MMP-2) and MMP-9 inhibitors. As such, they are described as...

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BioWorld Asia

BioWorld Asia briefs for April 14, 2026

Selective CBL-B inhibitor with improved safety profile disclosed

BioWorld Science

CBL-B is a RING-type E3 ubiquitin ligase that acts as a negative regulator of T-cell activation, contributing to immune homeostasis by limiting excessive immune...

MSD discloses new HCN1/2 blockers

BioWorld Science

Merck Sharp & Dohme LLC (MSD) has synthesized new indazole derivatives acting as potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1...