Shenzhen Zhongge Biotechnology identifies new NLRP3 inflammasome inhibitors

Sep. 12, 2024

Shenzhen Zhongge Biotechnology Co. Ltd. has discovered NLRP3 inflammasome inhibitors reported to be useful for the treatment of cancer, liver, cardiovascular, inflammatory, renal, metabolic and neuroinflammatory disorders.

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Inhibiting the NLRP3 inflammasome for cognitive impairment, stroke

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QC-6352 is a small molecule developed to inhibit the histone demethylase 4 (KDM4) that has shown potent antitumoral activity and which has a derivative named...

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First-in-class pan-inflammasome blocker for hidradenitis suppurativa

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SCAN is core circuit affected in Parkinson’s disease

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Parkinson’s disease is a neurodegenerative disorder that affects movement, and tremor is one of its signatures. But it is a much more wide-ranging disorder, and...