Alzheimer’s disease can be divided into multiple subtypes based on gene expression patterns, investigators at the Mount Sinai School of Medicine reported in the Jan. 6, 2021, issue of Science Advances. The work, corresponding author Bin Zhang told BioWorld, is “the first major finding of subtypes in Alzheimer’s disease.”

LONDON – A new national consortium of virologists has been set up to systematically assess how mutations in SARS-CoV-2 affect key outcomes such as effectiveness of vaccines and therapies, transmissibility of the virus and the severity of COVID-19 infections. Now is the critical time to do this, as the level of both natural and vaccine-conferred immunity that might drive natural selection is increasing, said Wendy Barclay, head of the department of infectious disease at Imperial College London, who is leading the G2P-UK (Genotype to Phenotype-UK) project.

BioWorld looks at translational medicine, including: With partner in crime, MYC repairs DNA breaks.

Aging, which is associated with various pathologies such atherosclerosis and cancer, is characterized by an accumulation of senescent cells. Cellular senescence blocks cell proliferation, but it decreases the health of the old by littering tissues with dysfunctional senescent cells.

Alzheimer’s disease can be divided into multiple subtypes based on gene expression patterns, investigators at the Mount Sinai School of Medicine reported in the Jan. 6, 2021, issue of Science Advances. The work, corresponding author Bin Zhang told BioWorld, is “the first major finding of subtypes in Alzheimer’s disease.”

BioWorld looks at translational medicine, including: Cellular underpinnings of allergen immunotherapy success.

BioWorld looks at translational medicine, including: New causal gene for chronic kidney disease; New classification scheme for glioblastomas.