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Leukemia illustration

Nociceptive neurons shown to boost hematopoiesis

Dec. 28, 2020
By John Fox
A U.S. study has shown for the first time that enhancing signals from the nociceptive nervous system could provide new approaches to improve the collection of hematopoietic stem cells (HSCs) for treating cancers of the blood and bone marrow.
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Clostridium difficile bacteria

CUHK develops rapid microrobotic diagnostic system for multiple pathogens

Dec. 23, 2020
By David Ho
HONG KONG – A research team at the Chinese University of Hong Kong (CUHK) has developed a fully automated, low-cost and rapid microrobotic diagnostic system that can be used with multiple pathogens, including COVID-19. The system works by integrating fluorescent microrobots with an external magnetic actuation system to detect pathogens in patient samples.
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BioWorld MedTech’s Orthopedics Extra for Dec. 23, 2020

Dec. 23, 2020
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: Remote monitoring leads to fourfold decline in returns to hospital after joint surgery; Researchers identify rare genetic bone disorder through massive sequencing methods; Orthogrid Systems says data support the use of its technology for orthopedic surgery; Exercise may protect bone health after weight loss surgery.
Read More
Prostate cancer cells

HSF1 inhibition directly targets treatment-resistant prostate cancer

Dec. 23, 2020
By John Fox
Scientists at Duke University School of Medicine in Durham, North Carolina, have developed a small-molecule inhibitor of the cellular stress-protective transcription factor, heat-shock factor 1, which showed developmental promise against treatment-resistant prostate cancer and other cancers.
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Bacteria in petri dishes

Inflammatory protein can distinguish between good and bad microbes

Dec. 23, 2020
By Subhasree Nag
Investigators at Leeds University have discovered that the proinflammatory cytokine IL-36gamma acts as a global early sensor of pathogenic invasion and discriminator of pathogenic and harmless microbes.
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BioWorld MedTech’s Oncology Extra for Dec. 22, 2020

Dec. 22, 2020
By Mark McCarty and Anette Breindl
Keeping you up to date on recent developments in oncology, including: Multicancer screening paradigm bolstered in new study; Potentiating PARP inhibitors; New non-viral vector siRNA approach described; NICE nods to combo therapy for HCC.
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newborn-infant-baby-feet.png

Stem cell-derived vesicles protective against neonatal hemorrhage

Dec. 22, 2020
By John Fox
Korean researchers at Sungkyunkwan University in Seoul have demonstrated that regenerative medicine using multipotent mesenchymal stem cell-derived extracellular vesicles could mitigate intraventricular hemorrhage-induced brain damage in newborn rats.
Read More
Lung cancer illustration

Tumors, metastases activate mTOR in different ways

Dec. 21, 2020
By Anette Breindl
Investigators at KU Leuven have discovered that although mTOR signaling was important in primary breast tumors and lung metastases alike, the signals that activated mTOR were different between the two, and mTOR signaling could be inhibited through different mechanisms.
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BioWorld MedTech’s Cardiology Extra for Dec. 21, 2020

Dec. 21, 2020
By Liz Hollis
Keeping you up to date on recent developments in cardiology, including: Biomarkers can forecast the development of incident heart failure; Mouse model helps researchers find MAARS lncRNA; Heart disease deaths rise in age of COVID-19.
Read More
HCC response to TARE

Microbubbles enhance response to TARE in liver cancer

Dec. 18, 2020
By Annette Boyle
Researchers at Thomas Jefferson University have found that using ultrasound to pop microbubbles already present in a contrast agent nearly doubled liver tumor response to transarterial radioembolization. The procedure raised no safety concerns and increased the likelihood of patients receiving a liver transplant.
Read More
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