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BioWorld - Saturday, December 27, 2025
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GM-CSF

Immune response research shows GM-CSF plays role in COVID-19 severity

March 11, 2021
By Nuala Moran
LONDON – The largest study of its kind to date has identified new biomarkers of inflammation that are both indicators of severe COVID-19 infection and distinguish it from severe influenza.
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HIV-infected T cells
Bench Press

Many elite controllers at HIV’s ground zero

March 11, 2021
By Anette Breindl
BioWorld looks at translational medicine, including: Fungal culprit in Crohn’s disease; Targeting membrane protein starves pancreatic tumors; Linking antiphospholipid antibodies to autoimmunity.
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CROI 2021: Sending HIV into the gene desert could be path to functional cure

March 10, 2021
By Anette Breindl
Curing HIV remains a dream for now, but it is clearly not a pipe dream. One of the challenges for developing a vaccine is that there is no natural immune response to model such a vaccine on. Over time, an untreated HIV infection will almost certainly kill its host. However, there is a group of elite controllers – people who, although they cannot eliminate the virus, manage to keep it in check.
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BioWorld MedTech’s Orthopedics Extra for March 10, 2021

March 10, 2021
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: Injectable porous scaffolds promote better, quicker healing after spinal cord injuries; Researchers grow most lifelike bone yet from woven cells; Rapid 3D printing method moves toward 3D-printed organs; Study links kidney stones with bone problems.
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Ultrasound set-up used in obesity and inflammation study

Liver-focused ultrasound stimulation could reduce obesity and inflammation

March 9, 2021
By Annette Boyle
Stimulating the liver with focused ultrasound decreased obesity, chronic inflammation and metabolic dysfunction in preclinical studies, reported GE Research and the Feinstein Institutes for Medical Research, the research arm of Northwell Health. In a study published in Scientific Reports, researchers demonstrated that nerve modulation with ultrasound in mice helped regulate neurons involved in food intake, glucose regulation and metabolism without negative side effects.
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Cell-to-cell interaction as viewed through holotomography technology

KAIST continues development of 3D holotomography technology, on the back of CAR T study success

March 9, 2021
By Gina Lee
HONG KONG – The Korea Advanced Institute of Science and Technology (KAIST) is making headway with its 3D holotomography technology, which enables a more accurate and systematic way to view cell-to-cell interactions. This could be a game changer for assessing cell therapy.
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BioWorld MedTech’s Oncology Extra for March 9, 2021

March 9, 2021
By Mark McCarty and Anette Breindl
Keeping you up to date on recent developments in oncology, including: USPSTF lowers recommended starting age for lung cancer screening; Suppression of collagen production boosts production of Cxcl5; Immigrants from China face barriers to cancer screening.
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HIV 3D model

At CROI, two-way street between HIV and SARS-CoV-2

March 9, 2021
By Anette Breindl
In 2020, the Conference on Retroviruses and Opportunistic Infections (CROI) was the first medical conference to go virtual, with two days advance warning, when news of infections resulting from a Biogen Inc. conference with about 150 attendees made it abundantly clear that SARS-CoV-2 was circulating, well, probably everywhere.
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Pancreas

IL-17 receptor's "B team" may be pancreatic cancer target

March 9, 2021
By John Fox
Taiwanese researchers have elucidated the signaling mechanism downstream of IL-17 receptor B and shown that its blockade using a neutralizing antibody reduced pancreatic cancer tumorigenesis and metastasis, while prolonging the life of tumor-bearing mice.
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BioWorld MedTech’s Cardiology Extra for March 8, 2021

March 8, 2021
By Mark McCarty
Keeping you up to date on recent developments in cardiology, including: TAVR patients at low surgical risk still ahead vs. SAVR, but thrombosis a concern; Heart failure numbers nearly doubled between 1990 and 2017; COVID exerting large effect on heart health.
Read More
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