A study of the epigenetic enzyme Pr-set7/Set8 by researchers at Duke-NUS Medical School in Singapore has shown it to play a key role in stimulating neural stem cells (NSCs) from their quiescent state, enabling their proliferation and the generation of new neurons.

Organoids grown from cholangiocytes – the epithelial cells of the bile duct – are poised to be used in ex vivo cell therapy to increase the number of donated livers that are suitable for transplant, and also for direct bile duct repairs. The organoids have been shown to be effective in correcting defects in mouse models and in perfused donated livers. They are now being tested in large animal models.

BioWorld looks at translational medicine, including: Fighting Staphylococcus with Staphylococcus.

There is a fundamental disconnect between how rapidly antidepressants act molecularly, and how slowly they act clinically.

BioWorld looks at translational medicine, including: Classifying variants of unknown significance; Platelets release antigenic DNA in lupus; Intracranial samples give glimpse into stroke response.

Researchers at the University of California San Diego (UCSD) have taken wearables to a new level with a soft skin patch that integrates functions currently siloed in continuous glucose monitors, wearables, wellness apps and hospital monitors. The all-in-one patch can be worn on the neck to continuously track blood pressure, heart rate, glucose, lactate, alcohol and caffeine.

Organoids grown from cholangiocytes – the epithelial cells of the bile duct – are poised to be used in ex vivo cell therapy to increase the number of donated livers that are suitable for transplant, and also for direct bile duct repairs.