For depression, and other mental health disorders, the era of precision medicine has yet to arrive. Symptoms are “very poorly reflective of the underlying biology,” Amit Etkin told BioWorld. Depression can manifest through multiple different symptoms that differ both between and within cultures.

BioWorld looks at translational medicine, including: CD47 knockout improves antitumor vaccine; Multiple edits make for durable T cells; Endothelial cells have functional deficits in progeria; Myelin is deregulated in autism spectrum disorder; More enhancers suggest more pathogenicity: study; Just the vesicles, please; Distinguishing real from backseat drivers; Blocking bad bone; Plexin D1 is receptor and mechanosensor in 1; Monocytes have it both ways in DMD.

The drug screens prompted by the SARS and MERS outbreaks have been useful for quickly identifying drug candidates. But in terms of their epidemiology, “SARS and MERS were different from this coronavirus,” Allison McGeer explained at a Feb. 3 webinar by Evercore ISI.

LONDON – The genomes of 38 different tumor types and the 47 million mutations that fostered their growth are revealed in unprecedented detail in 23 studies published in Nature and other journals on Feb. 6, 2020.

At this very early point in the emerging 2019-nCoV outbreak, knowledge about the virus is insufficient to predict what shape that outbreak will ultimately take. But knowledge about the virus is accumulating at remarkable speed, and experience with other viruses is helping to shape the response to the newest coronavirus threat. 2019-nCoV, sometimes called Wuhan coronavirus after its source, is the third coronavirus after SARS-CoV and MERS-CoV with the potential to cause serious illness and death that has emerged since the beginning of the 21st century.