This week’s report of remissions in three advanced leukemia patients after immunotherapy has generated quite a lot of excitement in the media – which, in turn, has led to some backlash amongst the twitterati and in the blogosphere, noting that two complete remissions plus a partial one don’t make a blockbuster. Or anything, really, that will be broadly useful within the next few years. Mainly, when I look at these controversies, I am grateful that I write for such a smart audience. If you are reading this blog, chances are that you work in the biopharmaceutical industry – and if...

As a biotech junkie, I’ll admit I was shocked to the core by Dendreon Corp.’s second-quarter admission that prostate cancer vaccine Provenge (Sipuleucel-T) is thus far not succeeding commercially. (See BioWorld’s news bulletin for details.) The most shocking part? Analyst and investor assumptions that Provenge’s poor performance is due not to reimbursement hurdles, as Dendreon claimed, but to an underlying lack of demand. Doctors and patients don’t want to use the product. Come again? Are you serious? Provenge is the first and only therapeutic cancer vaccine ever to gain FDA approval. I don’t have to tell anyone in the biotech...

The American Society of Clinical Oncology (ASCO) Annual Meeting kicked off the month of June as, arguably, the biggest event in the life sciences milieu, with 30,000-plus attendees and an inconsistent mélange of dispiriting and heartening news and data, while the Biotechnology Industry Organization (BIO) concluded the month with half that attendance, but with immeasurably more enthusiasm, excitement and expectations. Don't get me wrong — both events are excellently produced and loaded with germane details; however, when my restless mind sees differences, nothing is above satirizing. It's like Halloween for the health care industry vs. a birthday celebration for biotechnology....

BioWorld Today Contributing Writer   If you do a web search on the term “cancer cure,” you’ll get pages and pages of conspiracy theories, alternative medicine sites, and home-cooked “natural” remedies. Some of them, like baking soda and maple syrup (I kid you not) are probably harmless. Some of them cross the line into deception. But what you won’t find, as you click through pages and pages of snake oil, is a legitimate, mainstream medical site with information on curing cancer. The focus is on “controlling” the disease, “inducing” remission, maintaining “complete response,” increasing “overall survival,” and...

It looked Monday as if two of biotech’s long-suffering names might finally be biting the dust. Genta Inc. threw in the towel on beleaguered antisense drug Genasense (oblimersen sodium), after a final analysis of a Phase III melanoma trial – and a previous Phase III melanoma trial, and a Phase III chronic lymphocytic leukemia trial, and a Phase III multiple myeloma trial, and a melanoma approval bid, and a CLL approval bid, and a second CLL approval bid – failed. Meanwhile La Jolla Pharmaceutical Co., which already abandoned lupus drug Riquent (abetimus sodium) after years of mixed data and failed...