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Home » Topics » Science » Organoids

Organoids
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Koreabio Humanase KOH Sungho
Drug design, drug delivery and technologies

FDA shift from animal testing fuels organoid, organ-on-chip demand

May 14, 2025
By Marian (YoonJee) Chu
The U.S. FDA’s decision to phase out animal testing for INDs is driving a new market of alternative, nonanimal testing technologies like organoids and organs-on-a-chip, speakers at Bio Korea 2025 said.
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DNA and silhouette
Genetic/congenital

Organoids plus gene editing bring insights into pediatric metabolic disease

May 8, 2025
By Anette Breindl
No Comments
“I’m a pediatrician in metabolic diseases, and every day in my clinical work I’m confronted with our lack in effective therapies for our patients.” That was the sobering introduction by Sabine Fuchs in her talk at the 2025 Congress of the European Association for the Study of the Liver in Amsterdam this week. The nature of metabolic diseases makes it difficult to develop treatments for them. “There are over 1,500 diseases known by now, and it is just very difficult to develop therapies for each and every individual rare disease.”
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D-rendered image showing atlas of human embryonic skeletal development
Drug design, drug delivery & technologies

More than 100M cells included in the human cell atlas

Nov. 26, 2024
By Mar de Miguel
An international consortium of thousands of scientists is creating the Human Cell Atlas, a three-dimensional map of all the cells in the body. The goal is to understand all the cells that make up human tissues, organs and systems, which will enable multiple medical applications. This collection of cell maps is openly available for navigation at single-cell resolution, identified through omics analyses that reveal the tridimensional distribution of each cell.
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D-rendered image showing atlas of human embryonic skeletal development
Drug design, drug delivery & technologies

More than 100M cells included in the human cell atlas

Nov. 21, 2024
By Mar de Miguel
An international consortium of thousands of scientists is creating the Human Cell Atlas, a three-dimensional map of all the cells in the body. The goal is to understand all the cells that make up human tissues, organs and systems, which will enable multiple medical applications. This collection of cell maps is openly available for navigation at single-cell resolution, identified through omics analyses that reveal the tridimensional distribution of each cell.
Read More
Illustration of ovaries and uterus with endometriosis
Obstetrics

(Modest) funding increases bring endometriosis discovery impetus

Aug. 9, 2024
By Nuala Moran
After decades of being woefully under-diagnosed and all but ignored by the biotech and pharma industry, recent advances in understanding its complex etiology could be opening the way to new treatments for endometriosis. Impetus is coming from (modest) increases in funding for basic research, such as the Biden administration’s $200 million for women’s health research and NIH grants under an ‘Advancing cures and therapies and ending endometriosis diagnostic delays’ call announced in March of this year.
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3D model, X-rays of spine
Musculoskeletal

Astellas and Osaka University collaborate on cartilage organoid cell therapy for intervertebral disc degeneration

July 22, 2024
Astellas Pharma Inc.’s subsidiaries Astellas Institute for Regenerative Medicine (AIRM) and Universal Cells Inc. have entered into a research collaboration with Osaka University to develop a pluripotent stem cell-derived cartilage organoid cell therapy for the treatment of intervertebral disc degenerative disease.
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Illustration of thymus in relation to lungs and thyroid
Immune

Fibrobiologics’ artificial thymus organoid restores immune function in SCID mouse model

June 26, 2024
Fibrobiologics Inc. has announced the development of a novel artificial thymus organoid that can restore immune function in a severe combined immunodeficiency (SCID) mouse model.
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3D illustration of organoid models in a petri dish
Neonatal/Pediatrics

3D organoids arising from amniotic fluid cells may be a potent prenatal tool

March 8, 2024
By Xavier Bofill Bruna
Organoids are 3D models created from human stem cells and resemble fetal tissues. In an article published in Nature Medicine on March 4, 2024, researchers from University College London provided details on the possibility of generating organoids from epithelial cells collected from amniotic fluid without terminating the pregnancy.
Read More
Neonatal/Pediatrics

3D organoids arising from amniotic fluid cells may be a potent prenatal tool

March 5, 2024
By Xavier Bofill Bruna
Organoids are 3D models created from human stem cells and resemble fetal tissues. In an article published in Nature Medicine on March 4, 2024, researchers from University College London provided details on the possibility of generating organoids from epithelial cells collected from amniotic fluid without terminating the pregnancy.
Read More
Parkinson's disease illustration showing neurons containing alpha-synuclein
Neurology/Psychiatric

Stem Pharm and Verge Genomics collaborate on disease model to validate Parkinson’s targets

Oct. 11, 2023
Stem Pharm Inc. and Verge Genomics (Verge Analytics Inc.) have established a collaboration to develop a disease model to validate novel targets identified by Verge for Parkinson’s disease.
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