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Home » Topics » Clinical

Clinical
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Cytomegalovirus in a human cell

Takeda reports success for maribavir in tough post-transplant CMV cases

Dec. 8, 2020
By Michael Fitzhugh
New phase III data on Takeda Pharmaceutical Co. Ltd.'s TAK-620 (maribavir) for the treatment of transplant recipients with tough-to-treat cytomegalovirus (CMV) infections met the trial's primary endpoint, setting the company up to file an NDA for the oral antiviral in the first half of next year.
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Vicore Pharma hopes rise on C21 COVID-19 data

Dec. 8, 2020
By Cormac Sheridan
DUBLIN – Top-line data from a placebo-controlled phase II trial of Vicore Pharma Holding AB’s angiotensin II type two receptor agonist, C21, provide preliminary evidence that the oral drug may provide benefit to patients with severe COVID-19 disease on top of steroid therapy.
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Astrazeneca, Oxford publish phase III COVID-19 vaccine data, confirming 70% efficacy

Dec. 8, 2020
By Nuala Moran
LONDON – The Oxford University team behind the development of Astrazeneca plc’s COVID-19 vaccine have become the first to publish full and complete interim phase III data in a peer-reviewed journal.
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In the clinic for Dec. 8, 2020

Dec. 8, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aldeyra, Altimmune, Arena, Astrazeneca, Axsome, Bellus, Cardior, Curis, Domain, Harpoon, Larimar, Monopar, Novaliq, Panbela, Sojournix, Vicore, Xenon.
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In the clinic for Dec. 7, 2020

Dec. 7, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: 9 Meters, Alx, Arch Oncology, Arcturus, Arcutis, Brickell, Cel-Sci, Cytokinetics, Dare, Eisai, Genetx, Hookipa, Inovio, KPB, Lyra, Magenta, Neurorx, Odonate, Relief, Relmada, Sarepta, Tonix, Ultragenyx, Ysopia.
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Cytomegalovirus in a human cell

Takeda reports success for maribavir in tough post-transplant CMV cases

Dec. 4, 2020
By Michael Fitzhugh
New phase III data on Takeda Pharmaceutical Co. Ltd.'s TAK-620 (maribavir) for the treatment of transplant recipients with tough-to-treat cytomegalovirus (CMV) infections met the trial's primary endpoint, setting the company up to file an NDA for the oral antiviral in the first half of next year.
Read More

Word of mouth: Cortexyme’s Alzheimer’s trial focuses on gum disease

Dec. 4, 2020
By Lee Landenberger
The independent data monitoring committee overseeing Cortexyme Inc.’s phase II/III trial of atuzaginstat (COR-388), a gingipain inhibitor for patients with Alzheimer’s disease, has recommended the study continue to its one-year endpoint.
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In the clinic for Dec. 4, 2020

Dec. 4, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: AB Science, Apeiron, Ascletis, Clover, Cortexyme, Precision, Takeda, Sutro.
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Patient in hospital bed

Enlivex shares climb, sparked by new COVID-19 data

Dec. 3, 2020
By Michael Fitzhugh
Shares of immunotherapy developer Enlivex Therapeutics Ltd. (NASDAQ:ENLV) climbed as much as 69% Dec. 3 after interim data showed the apparent benefits of its lead candidate, Allocetra, for severe and critical COVID-19 patients.
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Despite phase III failure of Zepzelca, Jazz and Pharmamar vow to forge ahead

Dec. 3, 2020
By Lee Landenberger
The phase III study of Zepzelca (lurbinectedin) as combination therapy from Jazz Pharmaceuticals plc and Pharmamar SA was a stumble, but the companies said they found plenty of encouraging data prompting them to continue development.
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