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Home » Topics » Clinical

Clinical
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In the clinic for Nov. 9, 2020

Nov. 9, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: 9 Meters, American Brivision, Amylyx, Aptevo, Arcturus, Bioarctic, Biomarin, Biontech, BMS, Calliditas, Celltrion, Corvus, Daewoong, EIP, Eisai, Entera Bio, Immunitybio, Inmune, Intellia, Leap, Nevakar, Noxxon, Pfizer, Pierre Fabre, Reata, Regenerx, Synact, Vallon, Viiv.
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Biontech, Pfizer COVID-19 vaccine gains 90% protection in phase III interim peek

Nov. 9, 2020
By Randy Osborne
Blocks with gears, lightbulb, target, magnifying glass

Zimmer Biomet beats consensus in Q3, withholds 2020 guidance

Nov. 6, 2020
By Meg Bryant
Zimmer Biomet Holdings Inc. fell in line with other orthopedic device companies that saw better than expected results for the 2020 third quarter. The company reported total revenue of $1.93 billion, up 1.1% from the same period in 2019.
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Humanigen’s twice as nice COVID-19 bump for lenzilumab

Nov. 6, 2020
By Lee Landenberger
Lenzilumab, the lead candidate from Humanigen Inc., has taken two large steps forward with positive interim phase III data and some support from the federal government. That, along with an Asia-Pacific region licensing from earlier in the week, has the relatively small company successfully “punching above our weight,” the CEO told BioWorld.
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Hepatitis B virus

Assembly shares plummet after key HBV therapy readout falls short

Nov. 6, 2020
By Michael Fitzhugh
Assembly Biosciences Inc., a company testing the limits of sustained virologic response in people with chronic hepatitis B virus infection after they discontinue treatment, said nearly all participants in an ongoing phase II study returned to having detectable viral loads after going off a regimen featuring the company's core inhibitor, vebicorvir.
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Patient in hospital bed

Canakinumab flunks phase III trial in COVID-19

Nov. 6, 2020
By Cormac Sheridan
DUBLIN – Canakinumab, an interleukin-1 beta (IL-1beta) inhibitor, has joined a growing list of immunomodulatory therapies that have failed to demonstrate efficacy in COVID-19. Novartis AG said that an interim analysis showed the drug did not meet the primary endpoint of clinical response.
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In the clinic for Nov. 6, 2020

Nov. 6, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Anavex, Assembly, Boehringer Ingelheim, Equillium, Homology, Humanigen, Janssen, Novartis, Pfizer, Puma, Seres, Viela.
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Canakinumab flunks phase III trial in COVID-19

Nov. 6, 2020
By Cormac Sheridan
Hands illustrating pain and inflammation

Active pipeline of potential new lupus therapies unfolding as ACR begins

Nov. 5, 2020
By Michael Fitzhugh
New updates from a dynamic late-phase systemic lupus erythematosus pipeline shared at this week's American College of Rheumatology annual meeting and beyond showed a robust field of potential new treatments nearing the finish line.
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In the clinic for Nov. 5, 2020

Nov. 5, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Abbvie, Actinium, Acurx, Agenus, Arch, Aveo, Boehringer, Cellectar, Cytomx, Eusa, Genmab, Madrigal, Neurorx, Novartis, Novo Nordisk, Radnor, Rhythm, Rubius, Synlogic.
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