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Home » Topics » Clinical

Clinical
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In the clinic for Nov. 2, 2020

Nov. 2, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Agenus, Aim, Aivita, Aligos, Arcutis, Astrazeneca, Curevac, Daiichi, Eli Lilly, Gritstone, Humanigen, Immunic, Incyte, Jounce, Mindmed, Novartis, Resverlogix, Revimmune, Rhythm, Shionogi, Sun, Symvivo, Tetra, Tiziana, UCB, Ultimovacs.
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Stem cells

Motix mobilizes Biolinerx shares as late-stage data favors drug

Oct. 30, 2020
By Michael Fitzhugh
An interim analysis of Biolinerx Ltd.'s phase III test of motixafortide for stem cell mobilization in multiple myeloma patients has paved what CEO Philip Serlin called the "most efficient path to registration" for the candidate, an antagonist of the chemokine receptor CXCR4.
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Pancreatic pit stop for Bellicum GoCAR-T; crew reduced but wheels still on

Oct. 30, 2020
By Randy Osborne
Despite bad news from a phase I/II dose-escalation trial in relapsed/refractory metastatic pancreatic cancer, Bellicum Pharmaceuticals Inc. is staying in the game, albeit with far fewer employees.
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In the clinic for Oct. 30, 2020

Oct. 30, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aligos, Axovant, Bellicum, Biolinerx, Cerevel, Lilly.
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New HS light dawning in Aurora, Chemocentryx heads for phase III

Oct. 29, 2020
By Randy Osborne
With avacopan’s PDUFA date in anti-neutrophil cytoplasmic antibody-associated vasculitis (ANCA vasculitis) set for next summer, Chemocentryx Inc. rolled out long-awaited, COVID-19-delayed top-line findings from the company’s phase II, 390-patient Aurora study testing the compound for hidradenitis suppurativa (HS).
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In the clinic for Oct. 29, 2020

Oct. 29, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Abbvie, Aerie, Affyimmune, Anheart, Annovis, Avillion, Biolinerx, Chemocentryx, Connect, Frequency, Hookipa, Humanigen, Immunomolecular, Kiniksa, Kintor, Leap, Leo, Lilly, Mallinckrodt, Moderna, Plus, Regeneron.
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In the clinic for Oct. 28, 2020

Oct. 28, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Abbvie, Allergan, Alx, Ampio, Aurinia, Boehringer, Castle Creek, Clinuvel, Finch, Galera, Gyroscope, Highlight, Orasis, Mediwound, Regentree, Therapeutics Solutions.
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Chinatrials

Chinatrials highlights the trials and tribulations of running studies now

Oct. 27, 2020
By Elise Mak
The Chinatrials roundtable went virtual this year and drew clinical trial experts to discuss state-of-the-art clinical trial design strategies, which are increasingly important in a more competitive clinical landscape.
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Australia’s Actinogen advances lead compound Xanamem in Alzheimer’s disease, fragile X syndrome

Oct. 27, 2020
By Tamra Sami
PERTH, Australia – Sydney-based Actinogen Medical Ltd. will advance its lead compound, Xanamem, into two proof-of-concept phase II studies in Alzheimer’s disease and fragile X syndrome.
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Topaz data crystallizing in SMA, Scholar Rock not Dragon its feet

Oct. 27, 2020
By Randy Osborne
Shares of Cambridge, Mass.-based Scholar Rock Holding Corp. closed Oct. 27 at $30.02, up $16.30, or 119%, on positive six-month interim analysis results from the Topaz phase II trial with inhibitor of myostatin activator SRK-015 in type 2 and type 3 spinal muscular atrophy, and CEO Tony Kingsley pointed to “a rich cascade of data ahead of us.”
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