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BioWorld - Monday, June 22, 2026
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ASH 2021: For fitusiran, efficacy is impressive but safety’s not there yet

Dec. 14, 2021
By Anette Breindl
Two trials presented at the annual meeting of the American Society of Hematology (ASH) showed that treatment with the antithrombin inhibitor fitusiran reduced the bleeding rate in patients with severe hemophilia by roughly 90%, regardless of whether they had type A or B, and whether they had developed antibodies to recombinant clotting factors.
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Conference data for Dec. 14, 2021: ASH

Dec. 14, 2021
New and updated preclinical and clinical data presented by biopharma firms at the American Society of Hematology annual meeting, including: Actinium, Adagene, Affimed, Agios, Allogene, Annexon, Aprea, Arcellx, Astrazeneca, Autolus, Beigene, Editas, Emmaus, Epizyme, Equillium, Fate, Freeline, Gamida, GBT, Genentech, Glycomimetics, GSK, Hutchmed, I-Mab, Imara, Kite, Kura, Sutro.
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Ivan-Dimov-CEO-and-co-founder-Orca-Bio-12-13

ASH 2021: Orca Bio’s Orca-T therapy slashes GvHD rates in bone marrow transplant patients

Dec. 14, 2021
By Cormac Sheridan
Orca Bio Inc. reported at the American Society of Hematology that cancer patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) who received its Orca-T cell therapy product achieved higher rates of survival without experiencing either relapse or chronic graft-vs.-host (GvHD) disease than those who received a conventional graft.
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CVL-218 shows promising potency and safety in preclinical models

Dec. 14, 2021

Targeting CXCL16 shows therapeutic effects in model of TNBC

Dec. 14, 2021

Liver humanized NSG-PiZ mouse model developed to test HBV antiviral therapies

Dec. 14, 2021

Sleep-seizure EEG associations in TgBDNF mouse model of epilepsy

Dec. 14, 2021

PRGN-3007 shows promise for treating mantle-cell lymphoma

Dec. 14, 2021

WNK2 is differentially expressed in MYD88-mutated Waldenstrom macroglobulinemia

Dec. 14, 2021

Conference data for Dec. 13, 2021: ASH

Dec. 13, 2021
New and updated preclinical and clinical data presented by biopharma firms at the American Society of Hematology annual meeting, including: Aleta, Allovir, Alx, Beigene, Bio-Path, Bluebird, BMS, Carsgen, Catamaran, CDR-Life, Cellectis, Celularity, Corvus, CTI, Epizyme, Forma, GBT, Genentech, Harpoon, Ichnos, IGM, Imago, Immunicum, Immunogen, Incyte, Janssen, Jazz, Kite, Loxo, Maat, Morphosys, Neoleukin, Novartis, Orca, Precision, Protagonist, Regeneron, Samsung, Sana, Schrodinger, Servier, Silence, Syndax, Tessa, Vincerx, X4.
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