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BioWorld - Sunday, December 14, 2025
Home » Topics » Conferences » American Society of Hematology

American Society of Hematology
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Conference data for Dec. 10, 2019: American Society of Hematology

Dec. 10, 2019
New and updated preclinical and clinical data presented by biopharma firms at the 61st American Society of Hematology annual meeting in Orlando, Fla.
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Red blood cells
ASH 2019

Forty Seven’s data eat up the market, with positive results in MDS and AML

Dec. 9, 2019
By Lee Landenberger
ORLANDO, Fla. – Data from two studies from Forty Seven Inc. announced at the American Society of Hematology (ASH) annual meeting moved the market in a major way Monday as the company stock (NASDAQ:FTSV) soared 111% to close at $30.43, up $15.99.
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ASH 2019

Constellation shares fall after myelofibrosis update, despite progress

Dec. 9, 2019
By Michael Fitzhugh
ORLANDO, Fla. – Preliminary data from a phase II test of Constellation Pharmaceuticals Inc.'s CPI-0610 in patients with myelofibrosis (MF), previewed to market adulation in November, got a full airing Monday at the American Society of Hematology (ASH) annual meeting.
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ASH 2019

Janssen’s Imbruvica improves survivability

Dec. 9, 2019
By Lee Landenberger
ORLANDO, Fla. – Not long past the opening of the American Society of Hematology’s (ASH) massive annual conference, Janssen Biotech Inc. released upbeat follow-up survivability data on Imbruvica (ibrutinib) from two studies and an integrated analysis evaluating Imbruvica in previously untreated patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
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ASH 2019

Autolus’ CAR T therapy is well-tolerated

Dec. 9, 2019
By Lee Landenberger
ORLANDO, Fla. – New phase I/II data from Autolus Therapeutics plc announced at the American Society of Hematology’s (ASH) annual conference show that AUTO-3, the first bicistronic CAR T targeting CD19 and CD22 followed by an anti-PD1, was well-tolerated in a phase I/II study.
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ASH 2019

ASH and FDA detail new advice on sickle cell trial endpoints

Dec. 9, 2019
By Michael Fitzhugh
ORLANDO, Fla. – In an effort to get sickle cell disease (SCD) researchers, drug developers, patients and regulators all on the same page, the American Society of Hematology (ASH) and the FDA have released new recommendations aimed at establishing uniform global standards for clinical trial endpoints to evaluate new therapies.  
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ASH 2019

Kura Oncology plans pivotal trial in rare form of PTCL

Dec. 9, 2019
By Michael Fitzhugh
ORLANDO, Fla. – Kura Oncology Inc., encouraged by new data on tipifarnib and positive feedback from the FDA, said Sunday that next year it will initiate a single-arm, phase II registration-directed trial of the candidate in angioimmunoblastic T-cell lymphoma (AITL), a rare and often aggressive form of peripheral T-cell lymphoma (PTCL).  
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ASH 2019

Identifying and sometimes removing treatment and research barriers

Dec. 9, 2019
By Lee Landenberger
ORLANDO, Fla. – While disparities remain in putting minority and older patients into clinical trials and being treated for blood cancers, there are successes in getting once-ignored patients into the mix so they can receive the same treatments as others. 
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CRISPR-Cas9
ASH 2019

Gene editing can move cell therapy from biplane to Boeing era

Dec. 9, 2019
By Anette Breindl
ORLANDO, Fla. – “The Wright brothers showed that you could fly a plane, but it wasn’t very far and it wasn’t very safe,” Wendell Lim told his audience at the 61st American Society of Hematology (ASH) annual meeting this weekend. “That’s where cell therapy is now.”
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ASH 2019

Genentech showcases new data on CD20-CD3 bispecific for tough-to-treat lymphomas

Dec. 9, 2019
By Michael Fitzhugh
ORLANDO, Fla. - Chimeric antigen receptor T (CAR T) cells have proved to be a major advance in treating patients with refractory B-cell malignancies so far. But, often, in approaching those issues "we solve one and we create another," Stephen Schuster, a doctor at the Abramson Cancer Center at the University of Pennsylvania in Philadelphia, told reporters at the 61st American Society of Hematology (ASH) annual meeting Saturday.
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