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Home » Topics » Deals and M&A » Development

Development
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Eye and financial charts

TOI story creates buzz in RP as Kiora seals $301M deal

Feb. 1, 2024
By Randy Osborne
Kiora Pharmaceuticals Inc.’s development and commercialization deal with Théa Open Innovation (TOI), a sister company of Laboratoires Théa, for KIO-301 in degenerative retinal diseases “takes a bit of an industry-standard type of approach” in terms of structure, said CEO Brian Strem.
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Cells of the human intestine
Gastrointestinal

Human organ atlas maps healthy and diseased tissues at the cellular level

July 20, 2023
By Mar de Miguel
The Hubmap consortium has released the atlas of three human organs, a cell-by-cell map based on overlaid images from microscopy and molecular data. Maps of the intestine, the kidney and the placenta, published in three simultaneous articles, have revealed the cellular morphology and architecture of these organs in healthy and diseased conditions.
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Day 4 embryoid showing an inner epiblast-like domain that has apico-basal polarity
Drug Design, Drug Delivery & Technologies

New human embryonic models bring hope for insights, but also lots of brouhaha

June 28, 2023
By Mar de Miguel
The development of an embryo in its early stages involves a series of processes in which cells interact and organize to form tissues. In humans, these stages are studied with animal models, stem cells and cell aggregates that mimic natural development phases, or with human embryos, depending on their availability and a strict protocol. Now, in back-to-back papers published online in Nature, scientists from Yale University and the University of Cambridge have two new embryonic models formed from human stem cells to study development after embryo implantation in the uterus.
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Scant backlash from NASH crash as Genfit scores $539M-plus Ipsen deal in PBC

Dec. 17, 2021
By Randy Osborne
Genfit SA’s global development and commercialization deal with Ipsen Pharma SA for phase III-stage elafibranor in primary biliary cholangitis (PBC) – plus a separate arrangement for rights to an asset earlier in development from Genoscience Pharma SA – represent “the logical next steps in the implementation of a strategy that we outlined to you about 18 months ago,” Genfit CEO Pascal Prigent said during a conference call with investors.
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JCR-Research-10-5

Takeda secures ex-U.S. rights to JCR Pharma’s Hunter syndrome treatment

Oct. 5, 2021
By David Ho and Gina Lee
Takeda Pharmaceutical Co. Ltd. and JCR Pharmaceuticals Co. Ltd. have negotiated a geographically-focused licensing deal to develop and commercialize JR-141 (pabinafusp alfa), a potential therapy for mucopolysaccharidosis type II, also known as Hunter syndrome.
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Sumitomo’s Sunovion and Otsuka sign $890M worldwide development collaboration deal for four neuropsychiatric compounds

Oct. 5, 2021
By David Ho
Sumitomo Dainippon Pharma Co. Ltd., its U.S.-based subsidiary Sunovion Pharmaceuticals Inc. and Otsuka Pharmaceutical Co. Ltd. have inked a global collaboration agreement to jointly advance four new compounds for serious neuropsychiatric conditions. Sunovion granted Otsuka rights to collaboratively develop and commercialize the four compounds worldwide. In return, Sunovion will receive an up-front payment of $270 million and up to $620 million in development milestone payments for the agents, with the potential for more depending on additional indications. It could also receive sales milestones from Otsuka.
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Ascentage co-develops Bcl-2 and BTK combination therapy for SLL/CLL with Astrazeneca

June 23, 2020
By Elise Mak
BEIJING – Suzhou, China-based Ascentage Pharma Group Inc. said on June 22 that it is working with Astrazeneca plc’s hematology R&D unit, Acerta Pharma, to develop a combination therapy of its Bcl-2 inhibitor, APG-2575, with Acerta's BTK inhibitor, Calquence (acalabrutinib). The first patient has been dosed in the U.S.
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Ascentage co-develops Bcl-2 and BTK combination therapy for SLL/CLL with Astrazeneca

June 22, 2020
By Elise Mak
BEIJING – Suzhou, China-based Ascentage Pharma Group Inc. said on Monday that it is working with Astrazeneca plc’s hematology R&D unit, Acerta Pharma, to develop a combination therapy of its Bcl-2 inhibitor, APG-2575, with Acerta's BTK inhibitor, Calquence (acalabrutinib). The first patient has been dosed in the U.S.
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Model of clamped vaccine antigen

CSL, University of Queensland partner with CEPI to bring COVID-19 vaccine to the clinic

June 9, 2020
By Tamra Sami
PERTH, Australia – Aussie biotech CSL Ltd. and the University of Queensland (UQ) have entered a development agreement with the Coalition for Epidemic Preparedness Innovations (CEPI) to accelerate development, manufacture and distribution of a COVID-19 vaccine candidate developed by the University of Queensland.
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Handshake with globe background and digital overlay

Innovent partners with Roche in multibillion-dollar deal targeting bispecifics, cell therapies

June 9, 2020
By Elise Mak
BEIJING – Suzhou, China-based Innovent Biologics Inc. is known in China as one of the first drugmakers to launch a PD-1 monoclonal antibody. Now, the company is moving to expand its product portfolio and enhance efforts in developing bispecific antibodies and cell therapies in a potential multibillion-dollar deal with pharma giant Roche Holding AG.
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