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BioWorld - Tuesday, April 14, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Regulatory data

Non-small-cell lung cancer therapies lead FDA approvals in May

June 19, 2020
May was a big month for developers of non-small-cell lung cancer (NSCLC) therapeutics, which accounted for 27% of the FDA approvals.
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IPO money

Genetron and Progenity: A pair of molecular Dx IPOs in oncology, prenatal raise $356M

June 19, 2020
By Stacy Lawrence
China-based precision oncology company Genetron Holdings Ltd. and prenatal molecular testing company Progenity Inc. each successfully priced an IPO. This is just the latest demonstration that molecular diagnostics is gaining real traction when it comes to investment.
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CAR T cells attacking senescent cells

CAR T cells target senescence marker, ameliorate cancer, fibrosis

June 19, 2020
By Anette Breindl
By targeting chimeric antigen receptors (CARs) to a senescence marker, researchers at Memorial Sloan-Kettering Cancer Center have developed a CAR T cell that had beneficial effects in mouse models of both liver fibrosis and lung cancer.
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Foundation CDx1

Second tumor-agnostic approval (further) broadens Keytruda’s reach

June 19, 2020
By Anette Breindl
On June 17, the FDA approved checkpoint blocker Keytruda (pembrolizumab, Merck & Co. Inc.) “for the treatment of adult and pediatric patients with unresectable or metastatic tumor mutational burden-high (TMB-H) [?10 mutations/megabase (mut/Mb)] solid tumors, as determined by an FDA-approved test, that have progressed following prior treatment and who have no satisfactory alternative treatment options.” 
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Amgen begins phase III trial with AMG-510 for NSCLC with KRAS p. G12c mutation

June 19, 2020

FDA grants accelerated approval to Tazverik for relapsed/refractory follicular lymphoma

June 19, 2020

New androgen and/or glucocorticoid receptor antagonists synthesized at Nuvation Bio

June 19, 2020

Nimbus Lakshmi identifies new TYK2 inhibitors

June 19, 2020

Merck & Co. discovers adenosine receptor A2A and/or A2B antagonists

June 19, 2020

Clinical activity seen with bomedemstat in phase II study in advanced myelofibrosis

June 19, 2020
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