Spark Biopharma Inc. has prepared and tested stimulator of interferon genes protein (STING; TMEM173) agonists that are reported to be useful for the treatment of cancer.
Mitogen-activated protein kinase kinase kinase 13 (MAP3K13; LZK) inhibitors reported to be useful for the treatment of cancer have been described in a recent U.S. Department of Health and Human Services patent.
Research at KHR Biotec GmbH has led to the development of eukaryotic initiation factor 4A (elF4A) and GTPase mutant inhibitors potentially useful for the treatment of cancer, craniofacial syndrome and neurofibromatosis type I.
Researchers from Shanxi Medical University and affiliated organizations presented data from a study that aimed to analyze the expression and prognostic value of mitochondrial-related genes in patients with stomach adenocarcinoma (STAD).
Prostate cancer is the second most prevalent solid tumor in men and the fifth leading cause of cancer mortality in men worldwide. One of the proteins overexpressed in prostate cancer is serine/threonine-protein kinase PIM-1. There is evidence about the potential role of PIM-1 as a target in prostate cancer and the effect in cellular apoptosis that reducing levels of PIM-1 through its inducers JAK2/STAT3 may exert.
Captor Therapeutics SA has offered an update on its lead programs CT-01, CT-02 and CT-05. In the CT-01 program, CPT-6281 is currently undergoing IND/CTA-enabling studies with the first clinical trial expected to start at the end of the year. The first indication will be in hepatocellular carcinoma (HCC).
Hunan Warrant Pharmaceutical Technology Development Co. Ltd. has disclosed data on the identification of a novel small-molecule inhibitor of Bruton tyrosine kinase (BTK), HND-01, which was identified by modifying metabolite 20 of dasatinib and is being developed for the potential treatment of cancer.
Wigen Biomedicine Technology (Shanghai) Co. Ltd. has described 5-fluoro-7h-pyrrolo[2,3-d] pyrimidine compounds as Wee1-like protein kinase (Wee1) inhibitors potentially useful for the treatment of cancer.
Researchers from Centre National de la Recherche Scientifique, Inserm, Institut Curie and Uniwersytet im Adama Mickiewicza have prepared nitrogen-containing salinomycin derivatives reported to be useful for the treatment of cancer.
RSS
