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BioWorld - Friday, February 6, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Cancer

Erasca discovers new KRAS G12D inhibitors for cancer

Jan. 12, 2023
Erasca Inc. has described tricyclic GTPase KRAS (G12D mutant) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Beijing Innocare presents new SOS1 inhibitors for cancer

Jan. 12, 2023
Beijing Innocare Pharma Tech Co. Ltd. has divulged heterocyclic compounds acting as son of sevenless homolog 1 (SOS1) inhibitors reported to be useful for treatment of cancer.
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Cancer

Structural variants activate contiguous oncogenes

Jan. 12, 2023
The alteration of the genome by mutations that...
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Microscopic image of acute myeloid leukemia (AML) cells.
Immuno-oncology

CD123-targeted IgM-based bispecific xCD3 antibody, IGM-2537, exhibits potent tumoricidal activity with reduced cytokine release

Jan. 12, 2023
Approximately 20,100 new cases of acute...
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CAR T cell with implanted gene strand
Cancer

CD5-knockout anti-CD5 CAR T-cell product evaluated for relapsed and refractory CD5+ nodal T-cell lymphomas

Jan. 12, 2023
The relative 5-year survival for Non-Hodgkin...
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Cancer

Tuojie Biotech (Shanghai) describes new MALT1 inhibitors

Jan. 11, 2023
Tuojie Biotech (Shanghai) Co. Ltd. has identified mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) inhibitors reported to be useful for the treatment of cancer, inflammation and autoimmune diseases.
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Cancer cells
Cancer

National Institute of Pharmaceutical R&D divulges new TRKA inhibitors for cancer

Jan. 11, 2023
National Institute of Pharmaceutical R&D Co. Ltd. has synthesized high affinity nerve growth factor receptor (NTRK1; TRKA) and its mutant inhibitors reported to be useful for the treatment of cancer.
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3D illustration demonstrating antibody-drug conjugate.
Immuno-oncology

Ajinomoto and Exelixis sign license agreement to incorporate AJICAP technology into Exelixis ADCs

Jan. 11, 2023
Ajinomoto Co. Inc.'s Ajinomoto Bio-Pharma Services has announced a license agreement with Exelixis Inc. to incorporate AJICAP, Ajinomoto's proprietary site-specific bioconjugation and linker technologies, in the development of certain of Exelixis' antibody-drug conjugate (ADC) programs for cancer.
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Cancer cell and DNA
Immuno-oncology

Novel tumor cell-based therapeutic strategy shows promise in mouse cancer models

Jan. 11, 2023
A Harvard Medical School research team developed a bifunctional therapeutic vaccine strategy by transforming living tumor cells into a potent agent with direct tumor killing and immunostimulatory abilities.
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mRNA on digital background

Anima follows Takeda, Lilly deals with $580M Abbvie pact as Lightning strikes thrice

Jan. 10, 2023
By Randy Osborne
Since the advent of COVID-19 mRNA vaccines, the space has steadily grown hotter, a situation on which Anima Biotech Inc. has capitalized by way of a potential $580 million-plus deal with Abbvie Inc. to deploy mRNA biology modulators for three targets across oncology and Immunology.
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