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BioWorld - Saturday, May 9, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Cancer

French researchers present new 17β-HSD11-activated compounds

April 6, 2023
Centre National de la Recherche Scientifique and Université Paul Sabatier - Toulouse III have divulged alkynylcarbinols acting as 17β -hydroxysteroid dehydrogenase 11 (17β-HSD11; 17bHSD11; 17βHSD11)-activated compounds reported to be useful for the treatment of cancer, bacterial, fungal and parasitic infections.
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Cancer

Ubix Therapeutics describes new ENL degradation inducers

April 6, 2023
Ubix Therapeutics Inc. has identified proteolysis targeting chimeras (PROTACs) comprising cereblon (CRBN) ligands coupled to a protein ENL (MLLT1; YEATS1) targeting moiety via linker.
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Cancer

Shouyao Holdings divulges new DNA-PK inhibitors for cancer

April 6, 2023
Shouyao Holdings (Beijing) Co. Ltd. has synthesized DNA-dependent protein kinase (DNA-PK) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Arvinas Operations patents new PROTACs targeting ER, BRD4, AR and BRAF

April 6, 2023
Arvinas Operations Inc. has disclosed proteolysis...
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3D illustration and light micrograph of lung cancer.

US National Cancer Plan a potential windfall for diagnostics, diagnostic imaging

April 5, 2023
By Mark McCarty
The Biden administration has released the National Cancer Plan, a framework that expands and builds on the Cancer Moonshot program which came into being in 2016. The National Cancer Plan includes a strategies section that calls for development of new methods for detecting cancer and new imaging technologies for early cancer detection, just two provisions that would seem to portend good times ahead for companies that manufacture these products.
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Cancer cells

Proxygen partners with Merck in $2.6B molecular glue deal

April 5, 2023
By Caroline Richards
Merck & Co. Inc. has seen promise in Proxygen GmbH’s molecular glue degrader technology, agreeing to pay the drug discovery company up to $2.55 billion if specified research, development and commercial milestones are met.
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Regulatory icons
Radioactive revolution

Keeping up with the technology a growing task for regulators

April 5, 2023
By Mari Serebrov
The possibilities of cures for cancer and other tough-to-treat diseases and the ability to further personalize medicine are creating a lot of excitement about the future of radiopharmaceuticals as both therapy and diagnostics. To reach that future, industry and researchers will have to overcome a lot of challenges, not the least of which stem from the multiple government agencies involved in regulating the source material, development, distribution and use of radioactive drugs and devices.
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Glass vials with radioactive label
Radioactive revolution

Radiopharma pipeline gathers atomic speed

April 5, 2023
By Tamra Sami
The radiopharma field has garnered increasing attention in recent years due to big-ticket deals like Bayer AG's $2.9 billion acquisition of Algeta ASA and Novartis AG's nearly $6 billion spent on buying Advanced Accelerator Applications SA and Endocyte Inc. As a result, competition is ratcheting up and pipelines are exploding with new combinations of different drugs. The global radiopharmaceuticals market was estimated to be valued at $6.7 billion in 2020, a number expected to reach $11.5 billion by 2027, according to a 2022 William Blair report.
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Cancer

Astrazeneca discovers new PRMT5 inhibitors for cancer

April 5, 2023
Astrazeneca has described spirocyclic compounds acting as protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of cancer.
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Cancer

US researchers present new CDK4- and CDK6-targeting PROTACs for cancer

April 5, 2023
Researchers at Dana-Farber Cancer Institute Inc., Memorial Hospital for Cancer and Allied Diseases, Memorial Sloan Kettering Cancer Center and Stevens Institute of Technology have divulged proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase-binding moiety linked to cyclin-dependent kinase 4 (CDK4) and/or 6 (CDK6)-targeting moiety through a linker.
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