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BioWorld - Tuesday, April 28, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Concept art for targeting cancer
Immuno-oncology

China NMPA clears IND for Akeso’s trispecific antibody

March 16, 2026
No Comments
Akeso Inc.’s first-in-class trispecific antibody, AK-150, has received IND clearance from China’s National Medical Products Administration (NMPA) for clinical trials in patients with advanced solid tumors. Engineered using Akeso’s AI-driven drug discovery platform and its proprietary Tetrabody technology, AK-150 is a humanized anti-CSF-1R, ILT2 and ILT4 trispecific antibody that achieves multipathway blockade of both innate and adaptive immunity.
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Ha Gyong sik giving a presentation

Kanaph, Imbiologics to kick off 2026 Korea biotech, med-tech IPOs

March 13, 2026
By Marian (YoonJee) Chu
No Comments
Two biotech and three med-tech companies are slated for Kosdaq debuts this month, signaling a potential rebound for Korea financings in 2026. Kanaph Therapeutics Inc. will open with a ₩40 billion (US$26.99 million) raise and Imbiologics Corp. will debut with ₩52 billion. Additionally, Mezoo Co. Ltd., Cosmo Robotics Co. Ltd. and Recensmedical Inc. will launch IPOs.
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Stock market crash illustration

Immutep stock plummets 90% on efti phase III failure in NSCLC

March 13, 2026
By Tamra Sami
No Comments
Immutep Ltd.’s stock on Australia’s Securities Exchange plummeted nearly 90% on March 13 on the news that its phase III TACTI-004 trial evaluating eftilagimod alfa (IMP-321, efti) in first-line non-small-cell lung cancer was discontinued due to futility.
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Concept of business partnership
Cancer

Enodia acquires Sec61 assets from Kezar Life Sciences

March 13, 2026
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Enodia Therapeutics SAS has acquired Kezar Life Sciences Inc.’s assets from its Sec61-based discovery and development program, including clinical-stage KZR-261. Insights from Kezar’s Sec61-based programs will further strengthen Enodia’s core focus on Sec61-driven selectivity for targeting protein degradation.
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Cancer

Council of Scientific and Industrial Research describes anticancer agents

March 13, 2026
The Council of Scientific and Industrial Research has patented hybrid peptides acting as apoptosis inducer and reactive oxygen species (ROS) production enhancers designed for use in the treatment of cancer.
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Immuno-oncology

Chinese researchers patent anti-CDH17 immunoconjugates

March 13, 2026
A joint Changzhou Hengbang Pharmaceutical Co. Ltd., Hansoh Bio LLC and Shanghai Hansoh Biomedical Co. Ltd. patent discloses immunoconjugates comprising a monoclonal antibody targeting cadherin-17 (CDH17) covalently linked to cytotoxic drug.
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Earth from space

UK sets out regulatory pathway for biologics made in space

March 12, 2026
By Nuala Moran
No Comments
U.K. biopharma is working with the country’s space agency and Civil Aviation Authority (CAA) to plot a route for manufacturing biologic drugs in low earth orbit.
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Cancer

Zhejiang Pantheon Innovation Pharmaceutical patents NLRP3 inflammasome inhibitors

March 12, 2026
Zhejiang Pantheon Innovation Pharmaceutical Co. Ltd. has disclosed prodrugs of an NLRP3 inflammasome inhibitor compound. They are reported to be useful for the treatment of cancer and inflammation.
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Cancer

Roche synthesizes GTPase KRAS mutant inhibitors

March 12, 2026
Researchers at F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have discovered GTPase KRAS mutant inhibitors, particularly G12V, G12D and G12C mutant inhibitors. They are reported to be useful for the treatment of cancer.
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Cancer

PARG inhibitors disclosed in Recursion Pharmaceuticals patent

March 12, 2026
Recursion Pharmaceuticals Inc. has reported poly(ADP-ribose) glycohydrolase (PARG) inhibitors for the the treatment of cancer.
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