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Home » Topics » Disease categories and therapies » Dermatologic

Dermatologic
Dermatologic RSS Feed RSS

Plasmacure Plasoma pulser

Plasmacure secures funding for Plasoma wound healing tech

July 11, 2025
By Shani Alexander
Plasmacure B.V. secured €6 million (US$7 million) in series A funding for its Plasoma cold plasma system to treat complex wounds. The round was led by Venture Medical LLC, a U.S.-based provider of solutions for wound care, which also committed to spend over $10 million to support regulatory approval, reimbursement and U.S. market expansion of the Plasoma technology.
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3D rendering of skin cells and elastin with collagen layer
Dermatologic

GAS6-AXL axis activation results in scarless oral wound healing

July 11, 2025
By Xavier Bofill Bruna
No Comments
When injured, the human skin is repaired through a wound-healing process that forms fibrotic scar tissue. Scarring burdens patients at both the functional and esthetic levels, and scars in the craniofacial region in particular can be psychologically damaging for the individual. The principal limitation to developing effective scarring treatments is the limited understanding of the molecular mechanisms behind scar formation and the mechanisms that drive repair without scarring.
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Illustration of diabetic foot ulcer, cross section of wound
Dermatologic

FDA clears Eluciderm’s IND to begin clinical trial of ELU-42

July 9, 2025
No Comments
Eluciderm Inc. has received clearance from the U.S. FDA for its IND to conduct a phase I/IIa open-label study evaluating the safety and efficacy of ELU-42, a topical spray-on solution for open wound healing, in patients with diabetic foot ulcers (DFUs).
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Apogee’s Apex phase II reads out for APG-777 in atopic dermatitis

July 7, 2025
By Brian Orelli
No Comments
Apogee Therapeutics Inc. plans to enter a crowded atopic dermatitis market with established drugs, such as Dupixent (dupilumab, Regeneron Pharmaceuticals Inc. and Sanofi SA) and Ebglyss (lebrikizumab-lbkz, Eli Lilly and Co.), which are sold by much larger competitors. But the company thinks it can compete with its anti-IL-13 antibody, APG-777, thanks to the drug’s 77 day half-life that may allow it to be dosed only two to four times a year in the maintenance phase, compared to 13 to 26 injections per year for the established competitors.
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Dermatologic

New MRGPRX2 antagonists disclosed in Humanwell Healthcare patent

July 4, 2025
Humanwell Healthcare (Group) Co. Ltd. has divulged Mas-related G-protein coupled receptor member X2 (MRGPRX2) antagonists reported to be useful for the treatment of pain, autoimmune disease and dermatological disorders.
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Fibroblast illustration
Dermatologic

CYT-997 could be new approach for treating hypertrophic scars

July 4, 2025
No Comments
Chinese investigators have published data from studies investigating CYT-997 for the treatment of hypertrophic scars. CYT-997 is a tubulin polymerization inhibitor that reached phase II clinical development for the treatment of multiple myeloma and glioblastoma multiforme.
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Tetratherix Tetramatrix

Tetratherix lists on ASX in $25M IPO

June 30, 2025
By Tamra Sami
Tetratherix Ltd. raised AU$45 million (US$25 million) in its IPO on the Australian Securities Exchange (ASX:TTX) to support clinical development of its Tetramatrix polymer biomaterial platform to support bone regeneration, tissue spacing and tissue healing.
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Nektar juiced by rezpeg atopic dermatitis phase IIb data

June 24, 2025
By Randy Osborne
No Comments
Atopic dermatitis data from Nektar Therapeutics Inc. put investors even more in the mood for further results with rezpegaldesleukin (rezpeg), an IL-2 pathway agonist and regulatory T-cell proliferator, also in the works for severe to very severe alopecia areata.
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Wound Monitoring
Patents

Device for monitoring wounds without removing dressings

June 18, 2025
By Simon Kerton
Researchers from the University at Buffalo, the State University of New York (SUNY), filed for protection of their development of a new imaging technology that uses radar and AI to see through dressings to monitor wounds and other skin conditions.
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Andembry

New orphan drug, CSL’s garadacimab, cleared for hereditary angioedema

June 17, 2025
By Karen Carey and Tamra Sami
No Comments
Following a complete response letter issued last October over CMC issues, CSL Behring LLC gained U.S. FDA approval June 16 of its humanized anti-factor XIIa monoclonal antibody, garadacimab (CSL-312), to prevent hereditary angioedema attacks.
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