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BioWorld - Monday, June 15, 2026
Home » Topics » Hematologic, BioWorld

Hematologic, BioWorld
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Test tubes, dropper and capsules

Advancing the 'best of both' – BMS, Hengrui enter $15.2B deal

May 12, 2026
By Karen Carey
No Comments
In a deal potentially worth up to $15.2 billion, Jiangsu Hengrui Pharmaceuticals Co. Ltd. is joining efforts with Bristol Myers Squibb Co. to advance 13 early development programs in the fields of oncology, hematology and immunology. Shanghai-based Hengrui will hold exclusive rights in mainland China, Hong Kong and Macau, while Princeton, N.J.-based BMS will hold exclusive rights in the rest of the world. The deal includes four oncology/hematology assets from Hengrui, four immunology assets from BMS, and five assets that the two companies will jointly discover and develop.
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IPO and digital hologram with business icons

Hemab prices $301M in latest upsized biopharma IPO

May 1, 2026
By Jennifer Boggs
No Comments
Continuing biopharma’s IPO resurgence in 2026, Hemab Therapeutics Holdings Inc. priced an upsized offering of 16.75 million shares at $18 per share, the high end of its proposed price range, for gross proceeds of $301.5 million. Another $45 million could come if underwriters exercise their full overallotment.
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Sickle cell illustration

Novo’s Forma acquisition pays off with mitapivat competitor

April 20, 2026
By Brian Orelli
No Comments
Novo Nordisk A/S reported top-line results from the phase III Hibiscus study of its pyruvate kinase-R activator, etavopivat, which was acquired through the 2022 buyout of Forma Therapeutics Holdings Inc. The results set up a potential competition for patients afflicted by sickle cell disease with fellow PKR activator mitapivat from Agios Pharmaceuticals Inc.
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Cancer and blood cells

Hematopoietic stem cell research points to leukemia’s early roots

April 2, 2026
By Marian (YoonJee) Chu
No Comments
Hematopoietic stem cell research over the past century has shown that leukemia may be driven by an invisible hand of inflammation. The bone marrow and inflammation, then, may hold the keys to preventing blood cancers, according to John E. Dick’s plenary session at the 2026 Korean Society of Hematology International Conference, held March 26, 2026.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 1, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
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Lab sample and bone marrow illustration

Karyopharm phase III Sentry entry bucks rux in MF; to FDA next

March 24, 2026
By Randy Osborne
No Comments
What one analyst called an “intriguing” overall survival signal in phase III results has Karyopharm Therapeutics Inc. planning to meet with the U.S. FDA about a would-be sNDA filing for Xpovio (selinexor) in myelofibrosis (MF).
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Gold dollar sign inside gold cog

Sanofi licenses Sino Biopharm’s JAK/ROCK drug for $1.4B

March 4, 2026
By Tamra Sami
No Comments
On the heels of China’s approval of Sino Biopharmaceutical Ltd.’s rovadicitinib, Sanofi SA is now inlicensing the first-in-class dual JAK/ROCK inhibitor in a deal worth more than $1.4 billion.
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Primary myelofibrosis (PMF) cells in blood flow

China clears first JAK/ROCK drug for myelofibrosis

March 3, 2026
By Tamra Sami
No Comments
China’s National Medical Products Administration has approved Sino Biopharmaceutical Ltd.’s rovadicitinib, branded as Anxu, for first-line treatment of adults with intermediate- or high-risk primary myelofibrosis, as well as post polycythemia vera myelofibrosis or post-essential thrombocythemia myelofibrosis.
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After thalassemia win, Agios advances mitapivat, tebapivat in SCD

Feb. 13, 2026
By Marian (YoonJee) Chu
No Comments

Agios Pharmaceuticals Inc. is preparing to present a mixed bag of phase III Rise Up data to the U.S. FDA in hopes of “full approval” for mitapivat in sickle cell disease (SCD), which would make it its third indication in rare hematology.


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Lab mouse

Human-relevant models lining up to replace animal tests

Feb. 12, 2026
By Nuala Moran
No Comments
The pressure to replace animal testing with human-relevant assays that are more predictive of human-drug responses has now reached a tipping point, and there is a movement toward greater acceptance of these potentially more translatable tests.
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