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BioWorld - Thursday, December 25, 2025
Home » Topics » Disease categories and therapies » Infection

Infection
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Jerome Kim, of IVI, speaking at the Global Vaccine Forum
Global Vaccine Forum 2025

Self-amplifying mRNA technology underscored for next big pandemic

July 1, 2025
By Marian (YoonJee) Chu
No Comments
Experts in mRNA convened at the Global Vaccine Forum (GVF) 2025 to weigh the present and future of vaccine technology, including emerging innovations in self-amplifying mRNA (sa-mRNA) and drug delivery platforms.
Read More

ACIP questions remain unanswered

July 1, 2025
By Mari Serebrov
No Comments
While the first meeting of the U.S. CDC’s newly minted Advisory Committee for Immunization Practices (ACIP) is now recent history, questions about the makeup of the committee and its future direction remain unanswered.
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Syringe in front of Moderna logo

With new flu data, Moderna reconsiders its COVID combo

June 30, 2025
By Lee Landenberger
No Comments
Solid phase III efficacy results for Moderna Inc.’s seasonal influenza vaccine, mRNA-1010, may lead the company to resubmit a BLA for a flu/COVID-19 combo shot it has been developing. The top-line data showed Moderna’s flu vaccine produced a superior relative efficacy that was 26.6% higher than a comparator standard-dose seasonal influenza vaccine in people ages 50 and older.
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Infection

Pfizer discovers new nucleoprotein N inhibitors for RSV infection

June 30, 2025
Pfizer Inc. has described nucleoprotein N (respiratory syncytial virus [RSV]) inhibitors reported to be useful for the treatment of RSV infection.
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Infection

New PZA-mimicking prodrugs for tuberculosis disclosed in University of Maryland patent

June 30, 2025
University of Maryland has divulged pyrazinamide (PZA)-mimicking prodrugs reported to be useful for the treatment of tuberculosis.
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Infection

French scientists describe new treatment for cryptosporidiosis

June 30, 2025
Institut National Supérieur des Sciences Agronomiques de l’Alimentation et de l'Environnement has identified compounds reported to be useful for the treatment of cryptosporidiosis. 
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Infection

Shemyakin Institute of Bioorganic Chemistry divulges new antiviral photosensitizers for SARS-CoV-2

June 30, 2025
Shemyakin Institute of Bioorganic Chemistry has synthesized perylenylethynylphenol derivatives acting as photosensitizers for photodynamic therapy reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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U.S. Supreme Court

Supreme Court upholds ACA’s preventive care coverage

June 27, 2025
By Annette Boyle
The U.S. Supreme Court preserved the U.S. Preventative Services Task Force coverage mandate that requires payers to cover certain preventive services at no cost to patients in a 6-3 ruling. That’s very good news for many diagnostics companies including Exact Sciences Corp. and Guardant Health Inc. as well as companies that manufacture HIV pre-exposure prophylaxis (PReP) medications such as Gilead Sciences Inc.
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Jerome Kim, of IVI, speaking at the Global Vaccine Forum
Global Vaccine Forum 2025

Self-amplifying mRNA technology underscored for next big pandemic

June 27, 2025
By Marian (YoonJee) Chu
No Comments
Experts in mRNA convened at the Global Vaccine Forum (GVF) 2025 to weigh the present and future of vaccine technology, including emerging innovations in self-amplifying mRNA (sa-mRNA) and drug delivery platforms. “Breakthroughs in mRNA and next-generation vaccine platforms are revolutionizing how we prepare for and respond to global health challenges,” Jerome H. Kim, International Vaccine Institute (IVI) director general, told the audience in Seoul, South Korea, June 19.
Read More
3D illustration of leishmania parasite
Infection

Discovery and evaluation of new indole-dihydropyrimidinone derivatives for visceral leishmaniasis

June 27, 2025
No Comments
Visceral leishmaniasis is a fatal disease caused by the Leishmania parasite, affecting organs such as the liver and spleen. Visceral leishmaniasis is considered a neglected tropical disease and is estimated to cause between 50,000 and 90,000 cases and around 70,000 deaths per year.
Read More
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