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BioWorld - Tuesday, April 14, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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Illustration of HIV particles
HIV/AIDS

New multi-epitope HIV-1 vaccine based on virus-like particles engineered to enhance immune response

Feb. 7, 2025
The development of an effective HIV vaccine remains an urgent public health need due to the high genetic variability and rapid mutation rates of the virus, which limit the generation of broadly neutralizing antibodies.
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HIV/AIDS

Merck Sharp & Dohme describes new Gag polyprotein (HIV-1)/protein Pol dimerization inducers

Feb. 6, 2025
Merck Sharp & Dohme LLC has identified targeted activator of cell kill (TACK) compounds acting as Gag polyprotein (HIV-1)/protein Pol dimerization inducers reported to be useful for the treatment of HIV infection.
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FDA website and logo

Doctors group sues US CDC, FDA, HHS over data takedown

Feb. 5, 2025
By Mari Serebrov
When the U.S. CDC and FDA recently removed several webpages and datasets from their websites in compliance with a directive from the Office of Personnel Management, they broke the law and harmed public health and research, according to a lawsuit filed Feb. 4 by Doctors for America.
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Sen. Raphael Warnock at RFK confirmation hearing

Kennedy advances toward confirmation as HHS secretary

Feb. 4, 2025
By Mari Serebrov
Robert F. Kennedy Jr. moved a step closer Feb. 4 to becoming the next secretary of the U.S. Department of Health and Human Services (HHS). The Senate Finance Committee voted 14-13 along party lines to send Kennedy’s nomination to the Senate floor for confirmation. While “no” votes were expected from the 13 Democrats serving on the committee, a big question mark had hung over which way Sen. Bill Cassidy, R-La., would vote, given the comments he made at two committee hearings on the nomination. In the end, Cassidy voted along with his 13 Republican colleagues, offering no comment on his vote at the meeting.
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Vaxxas HD-MAP Administration

Vaxxas, CEPI advance program for thermostable mRNA vaccines

Feb. 4, 2025
By Tamra Sami
Vaxxas Pty. Ltd. and the Coalition for Epidemic Preparedness Innovations are progressing heat-stable, dried-formulation mRNA vaccines using Vaxxas’ needle-free high-density microarray patch.
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Infection

Shanghai Curegene Pharmaceutical divulges new Mpro inhibitors

Feb. 4, 2025
Shanghai Curegene Pharmaceutical Co. Ltd. has synthesized 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infections (COVID-19).
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RFK Senate-hearing2 1-29

One vote could keep RFK from getting out of committee

Feb. 3, 2025
By Mari Serebrov
Whether Robert F. Kennedy Jr. (RFK) advances in his quest to become the top health care voice in the Trump administration could come down to one vote – that of Sen. Bill Cassidy. The Louisiana doctor is one of 14 Republican members of the Senate Finance Committee, which is scheduled to vote Feb. 4 on whether to send Kennedy’s nomination as Health and Human Services secretary to the full Senate for confirmation. If all 13 Democrats on the committee vote against it, one no vote from a Republican could stop the process.
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3D illustration of leishmania parasite
Infection

Pharmacomodulation of 2-aminothiophene derivatives with antileishmanial activity

Feb. 3, 2025
Researchers from Universidade Estadual da Paraíba, Universidade Federal da Paraiba and affiliated organizations presented the design, synthesis and bio-evaluation of new small-molecule candidates for the treatment of leishmaniasis, a neglected tropical disease that affects approximately 12 million people in four continents.
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Photo of bird, H5N1 virus
Infection

Antibody prevents severe bird flu in macaques

Feb. 3, 2025
By Mar de Miguel
Scientists at the University of Pittsburgh have tested a broadly neutralizing antibody that binds the stem of a protein against H5N1 avian influenza, which prevented severe disease in nonhuman primates and was effective for at least 8 weeks. The scientists remark on the potential of the design developed by Astrazeneca plc against a possible outbreak of the influenza A virus.
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Female researcher wearing mask and safety glasses holding dropper

APACMed sees urgent need to harmonize regs for LDTs across APAC

Jan. 31, 2025
By Tamra Sami
Harmonized regulations for laboratory-developed tests (LDTs) across Asia Pacific are sorely needed at a time when LDTs continue to play a critical role in addressing unmet needs in the region, according to a recent whitepaper developed by APACMed.
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