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BioWorld - Saturday, February 4, 2023
Home » Topics » Inflammatory, BioWorld Science

Inflammatory, BioWorld Science
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Inflammatory

Philadelphia University describes new COX-2 inhibitors

Feb. 3, 2023
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Philadelphia University (Jordan) has synthesized 2,4-disubstituted-thieno[2,3-d]pyrimidines acting as prostaglandin G/H synthase 2 (COX-2) inhibitors.
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Inflammatory

Prazer Therapeutics presents new MAPK14 inhibitors

Feb. 1, 2023
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Prazer Therapeutics Inc. has identified mitogen-activated protein kinase 14 (MAPK14) inhibitors reported to be useful for the treatment of inflammatory disorders.
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Inflammatory

Novartis divulges new S1P3 receptor antagonists

Jan. 30, 2023
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Novartis AG has patented sphingosine 1-phosphate S1P3 receptor antagonists reported to be useful for the treatment of lung inflammation.
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Joint pain
Inflammatory

Discovery of multitarget inhibitors with anti-inflammatory and analgesic activities

Jan. 30, 2023
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Researchers from Hefei Industrial Pharmaceutical Institute Co. Ltd. presented the discovery and preclinical evaluation of novel multifunctional inhibitors as potential anti-inflammatory and analgesic agents.
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Inflammatory

Novel anti-inflammatory compound alleviates LPS-induced acute lung injury in vivo

Jan. 27, 2023
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Researchers from Wenzhou Medical University and affiliated organizations have reported the discovery and preclinical evaluation of novel anti-inflammatory compounds. Synthesis and optimization of a new series of 1-(4-(benzylsulfonyl)-2-nitrophenyl) derivatives resulted in the identification of compound [I] as the lead candidate.
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Inflammatory

UCB describes IL-17 modulators for autoimmune and inflammatory disorders

Jan. 26, 2023
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UCB SA has identified imidazotriazine derivatives acting as IL-17 modulators reported to be useful for the treatment of autoimmune and inflammatory disorders.
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Inflammatory

HM-266, a novel PD-1 agonist MAb with efficacy in models of inflammatory disease

Jan. 26, 2023
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Researchers from Meiji Seika Pharma Co. Ltd. and affiliated organizations reported the discovery and preclinical evaluation of a novel PD-1 agonist antibody, HM-266, being developed for the treatment of various inflammatory disorders, including autoimmune diseases.
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Inflammatory

Reservoir Neuroscience divulges new PTGER2 antagonists

Jan. 19, 2023
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Reservoir Neuroscience Inc. has disclosed prostaglandin E2 receptor EP2 subtype (PTGER2; EP2) antagonists reported to be useful for the treatment of inflammation.
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Inflammatory

University of Copenhagen patents new GPR84 antagonists

Jan. 16, 2023
No Comments
University of Copenhagen has divulged 4-hydroxypyridine and 4-hydroxyquinoline derivatives acting as G-protein coupled receptor 84 (GPR84) antagonists reported to be useful for the treatment of fibrosis, diabetes, inflammatory and cognitive disorders.
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Inflammatory

Cantargia completes toxicity study for IL1RAP-binding antibody CAN-10

Jan. 16, 2023
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Cantargia AB has completed a GLP toxicity study for its anti-inflammatory IL1RAP-binding antibody CAN-10, showing that CAN-10 was well tolerated when administered over 6 weeks.
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