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BioWorld - Monday, April 6, 2026
Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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In vivo imaging of integrin beta-2 activation enabled with humanized integrin beta-2 knockin mice

April 13, 2022

Neuropilin-2 suppression is possible approach for treating lymphatic malformations

April 13, 2022

Targeting NHE1 prevents lung fibrosis progression

April 11, 2022

NUAK1 inhibition as new antifibrotic treatment strategy

April 6, 2022

Gut reaction to rapamycin extends female fly lifespan

April 5, 2022

New NLRP3 inflammasome inhibitors identified at NodThera

March 31, 2022

Wuhan LL Science and Technology Development presents new MAPK8 inhibitors

March 30, 2022

Atom Bioscience planning phase III gout trial after encouraging mid-stage readout

March 29, 2022
By Doris Yu
Jiangsu Atom Bioscience and Pharmaceutical Co. Ltd., a company developing an oral a urate anion exchanger 1 inhibitor for the potential treatment of chronic gout, said results of a phase IIa trial show that its lead candidate, ABP-671, reduced serum uric acid levels to less than 6 mg/dL, below the clinically defined threshold of 7 mg/dL for hyperuricemia, or excess of uric acid in the blood, which leads to gout.
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Atom Bioscience planning phase III gout trial after encouraging mid-stage readout

March 25, 2022
By Doris Yu
Jiangsu Atom Bioscience and Pharmaceutical Co. Ltd., a company developing an oral a urate anion exchanger 1 inhibitor for the potential treatment of chronic gout, said results of a phase IIa trial show that its lead candidate, ABP-671, reduced serum uric acid levels to less than 6 mg/dL, below the clinically defined threshold of 7 mg/dL for hyperuricemia, or excess of uric acid in the blood, which leads to gout.
Read More
Outline of intestine and person holding stomach in painntestine on person holding stomach in pain

Pfizer’s $6.7B Arena buy looks sound after positive phase III readout from etrasimod

March 23, 2022
By Richard Staines
One of Pfizer Inc.’s last decisions of 2021 was to shell out $6.7 billion for San Diego’s Arena Pharmaceuticals Inc., a deal centered around the pipeline inflammatory disease pill etrasimod. A potential successor to Xeljanz (tofacitinib), the price New York-based Pfizer paid suggests blockbuster potential for etrasimod. Phase III results announced March 23 suggest Pfizer’s big acquisition, the fifth largest in biopharma in 2021, was money well spent.
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