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BioWorld - Wednesday, June 3, 2026
Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Doctor holding illustration of cross section of skin
Dermatologic

DXP-006 reduces disease severity in psoriasis models

April 10, 2026
No Comments
Researchers from Singlomics Zhuhai Danxu Biopharmaceuticals Co. Ltd. presented DXP-006, a humanized antibody targeting IL1RAP, a shared co-receptor required for IL-1, IL-33 and IL-36 cytokines.
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Inflammatory

Leonabio discovers new pannexin-1 inhibitors

April 9, 2026
Leonabio Inc. has patented new pannexin-1 (PANX1; MRS1) inhibitors described as useful for the treatment of inflammatory disorders, epilepsy and pain.
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Photo of pipette with test tube
Respiratory

LCC-6 characterized as an antifibrotic and copper chelator agent

April 9, 2026
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Copper overload within the body may lead to cancer, neurodegenerative diseases, inflammation or fibrosis, among others. Copper chelation is an effective strategy to counteract this potential overload; mitochondria play an important role, as they are the main copper-using organelles in the cells. Copper chelators have been developed, but they have shown some undesired off-target effects and low specificity, which suggests the need for new therapies in the field.
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Illustration of lymphocytes
Immune

Milestone under Cue and Boehringer Ingelheim collaboration

April 9, 2026
No Comments
Cue Biopharma Inc. has reached a preclinical milestone in its collaboration and license agreement with Boehringer Ingelheim Pharma GmbH & Co. KG, following the latter’s selection of a first compound for lead optimization. The milestone triggers a $7.5 million payment to Cue.
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Inflammatory

Forward Therapeutics patents new TNF-α inhibitors

April 8, 2026
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Forward Therapeutics Inc. has identified new TNF-α inhibitors potentially useful for the treatment of inflammatory disorders and autoimmune diseases.
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Spinal cord
Musculoskeletal

Fortitude unveils lead program for axial spondyloarthritis

April 8, 2026
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Fortitude Biomedicines Inc. has disclosed that its lead program, FORT-202, is a first-in-class T-cell-targeting bispecific antibody for the potential treatment of axial spondyloarthritis. As a bispecific antibody, FORT-202 is designed to address multiple disease-causing pathways and is expected to significantly improve therapeutic efficacy.
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Cancer and blood cells

Hematopoietic stem cell research points to leukemia’s early roots

April 7, 2026
By Marian (YoonJee) Chu
No Comments
Hematopoietic stem cell research over the past century has shown that leukemia may be driven by an invisible hand of inflammation. The bone marrow and inflammation, then, may hold the keys to preventing blood cancers, according to John E. Dick’s plenary session at the 2026 Korean Society of Hematology International Conference, held March 26, 2026.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 7, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
Read More
Cancer and blood cells

Hematopoietic stem cell research points to leukemia’s early roots

April 2, 2026
By Marian (YoonJee) Chu
No Comments
Hematopoietic stem cell research over the past century has shown that leukemia may be driven by an invisible hand of inflammation. The bone marrow and inflammation, then, may hold the keys to preventing blood cancers, according to John E. Dick’s plenary session at the 2026 Korean Society of Hematology International Conference, held March 26, 2026.
Read More
PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 1, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
Read More
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