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BioWorld - Sunday, February 22, 2026
Home » Topics » Disease categories and therapies » Musculoskeletal

Musculoskeletal
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New osteoarthritis risk variants and drug targets identified in large GWAS meta-analysis

Sep. 22, 2021

KLF5 inhibitor AM-80 ameliorates muscular atrophy in mice

Sep. 21, 2021

Lilly discovers TYK2 JH2 domain ligands

Sep. 8, 2021

Astellas stops dosing gene therapy for rare neuromuscular disease after trial's fourth SAE

Sep. 7, 2021
By Michael Fitzhugh
Astellas Pharma Inc. has halted further dosing of the experimental X-linked myotubular myopathy (XLMTM) gene therapy AT-132 (resamirigene bilparvovec) after one participant in the ongoing Aspiro study experienced a serious adverse event (SAE) of abnormal liver function.
Read More

IRF5 inhibition suppresses lupus-like disease in mice

Sep. 6, 2021

Glucocorticoid receptor agonist ADCs patented by AbbVie

Sep. 6, 2021

Astellas stops dosing gene therapy for rare neuromuscular disease after trial's fourth SAE

Sep. 1, 2021
By Michael Fitzhugh
Astellas Pharma Inc. has halted further dosing of the experimental X-linked myotubular myopathy (XLMTM) gene therapy AT-132 (resamirigene bilparvovec) after one participant in the ongoing Aspiro study experienced a serious adverse event (SAE) of abnormal liver function.
Read More

Eternity Bioscience patents new ADAMTS inhibitors

Sep. 1, 2021

Phase II trial of izokibep in ankylosing spondylitis commences dosing

Aug. 26, 2021

Clinical hold extended for ORTHO-R phase I/II study

Aug. 23, 2021
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