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Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Respiratory

PDGFR-β inhibitors reported in Actelion Pharmaceuticals patent

June 13, 2024
Actelion Pharmaceuticals Ltd. has identified pyrazolopyrrolopyridazines acting as platelet-derived growth factor receptor β (PDGFR-β, PDGFRB) inhibitors reported to be useful for the treatment of pulmonary arterial hypertension.
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FDA Orange Book

US court adopts FTC stance in Orange Book listing challenge

June 12, 2024
By Mari Serebrov
The U.S. FTC’s campaign against the Orange Book listing of patents claiming device components gained momentum when a federal judge in New Jersey ordered Teva Pharmaceuticals USA Inc. to delist five device patents pertaining to its Proair HFA (albuterol sulfate) inhaler.
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Lungs anatomy
Respiratory

US DoD grant supports Kevirx’s development of drug for acute lung injury

June 12, 2024
Kevirx Inc. has been awarded nearly $2 million in grant funding from the U.S. Department of Defense (DoD)’s peer-reviewed medical research program.
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Asia cityscape, map with Thailand under magnifier

Lotus acquires Teva Thailand to build Southeast Asian footprint

June 11, 2024
By Tamra Sami
Lotus Pharmaceutical Co. Ltd. is acquiring the Thailand business and commercial entity of Teva Pharma Thailand to expand its footprint in Southeast Asia.
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Asia cityscape, map with Thailand under magnifier

Lotus acquires Teva Thailand to build Southeast Asian footprint

June 10, 2024
By Tamra Sami
Lotus Pharmaceutical Co. Ltd. is acquiring the Thailand business and commercial entity of Teva Pharma Thailand to expand its footprint in Southeast Asia.
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deep breath ultrasound
Patents

Deep Breathe’s wearable AI-powered POC lung ultrasound imaging system

June 7, 2024
By Simon Kerton
London, Ontario-based Deep Breathe Inc. filed for protection of a wearable ultrasound sensor that is used to obtain ultrasound data, and digital ultrasound images are processed using a machine learning model to predict the probability of lung sliding and detection of pneumothorax (collapsed lung) if lung sliding is absent or deem it likely if lung sliding is present.
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AI-generated image of person in hazmat suit in poultry farm with chickens out of focus in the background
Infection

Preclinical H5 mRNA vaccine immunizes and prevents mortality

June 7, 2024
A preclinical trial in mice and ferrets of an experimental mRNA vaccine against the H5 highly pathogenic avian influenza (HPAI) virus generated neutralizing antibodies and prevented severe illness and mortality of the animals.
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sleep apena app
Patents

Researchers develop app to improve sleep apnea treatment adherence

June 6, 2024
By Simon Kerton
Researchers from the University of Chicago and Northwestern University have filed for protection of an mobile application to track individualized patient needs, engagement in continuous positive airway pressure machine use, and the correlation of risk behaviors to determine sleep apnea treatment progress.
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Respiratory

S1PR3 is target in acute respiratory distress syndrome

June 6, 2024
Excessive inflammatory response and endothelial barrier dysfunction are the two major pathophysiological changes in acute respiratory distress syndrome (ARDS). Sphingosine-1-phosphate S1P3 receptor (S1PR3) is a G protein-coupled receptor involved in the regulation of inflammation and vascular barrier function in some diseases, but its function in ARDS is not fully understood.
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Respiratory

New TGF-β receptor type-1 inhibitors revealed in Chiesi patent

June 5, 2024
Chiesi Farmaceutici SpA has divulged TGF-β receptor type-1 (TGFBR1; ALK5; SKR4; TβR-I) inhibitors reported to be useful for the treatment of idiopathic pulmonary fibrosis.
Read More
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